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中性粒细胞减少性小肠结肠炎:急性白血病一种罕见的并发症表现。

Neutropenic enterocolitis: a rare presenting complication of acute leukemia.

作者信息

Quigley M M, Bethel K, Nowacki M, Millard F, Sharpe R

机构信息

Laboratory Department, Naval Medical Center, San Diego, California 92134-1005, USA.

出版信息

Am J Hematol. 2001 Mar;66(3):213-9. doi: 10.1002/1096-8652(200103)66:3<213::aid-ajh1047>3.0.co;2-o.

Abstract

Neutropenic enterocolitis is a necrotizing inflammatory process with intramural infection that occurs predominantly in neutropenic patients. This syndrome is most frequently observed after chemotherapy for hematologic and solid tissue malignancies, but it can also be observed in a number of other clinical settings as well. Neutropenic enterocolitis can be a rare presenting complication of acute leukemia. We report a case of acute lymphoblastic leukemia that presented with abdominal pain due to neutropenic enterocolitis. The diagnostic and treatment challenges associated with this manner of presentation are discussed.

摘要

中性粒细胞减少性小肠结肠炎是一种主要发生在中性粒细胞减少患者中的伴有壁内感染的坏死性炎症过程。这种综合征最常见于血液系统和实体组织恶性肿瘤化疗后,但也可见于许多其他临床情况。中性粒细胞减少性小肠结肠炎可能是急性白血病罕见的首发并发症。我们报告一例因中性粒细胞减少性小肠结肠炎出现腹痛的急性淋巴细胞白血病病例。并讨论了与此种表现方式相关的诊断和治疗挑战。

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