Marc P, Devaux F, Jacq C
Laboratoire de Génétique Moléculaire, CNRS 8541, Ecole Normale Supérieure, 46 Rue d'Ulm, 75005 Paris, France.
Nucleic Acids Res. 2001 Jul 1;29(13):E63-3. doi: 10.1093/nar/29.13.e63.
The yeast Microarray Global Viewer (yMGV) is an on-line database providing a synthetic view of the transcriptional expression profiles of Saccharomyces cerevisiae genes in most of the published expression datasets. yMGV displays a one-screen graphical representation of gene expression variations for each published genome-wide experiment, allowing quick retrieval of experimental conditions affecting expression of this gene. yMGV also provides tools to isolate groups of genes sharing similar transcription profiles in a defined subset of experiments. Additionally, yMGV furnishes a set of statistical tools for critical assessment of published data. We therefore believe that yMGV is an efficient tool that affords a quick and comprehensive overview of microarray data and generates new gene classifications. As of 20 March 2001 the yMGV database contains 6 000 000 measurements, representing genome-wide expression comparisons of 932 experiments from 39 microarray publications. The yMGV interface is available at http://transcriptome.ens.fr/ymgv/.
酵母微阵列全局查看器(yMGV)是一个在线数据库,它能综合展示酿酒酵母基因在大多数已发表的表达数据集中的转录表达谱。yMGV为每个已发表的全基因组实验呈现一屏的基因表达变化图形表示,便于快速检索影响该基因表达的实验条件。yMGV还提供工具,用于在特定实验子集中分离具有相似转录谱的基因组。此外,yMGV提供了一组统计工具,用于对已发表的数据进行严格评估。因此,我们认为yMGV是一个高效的工具,能快速全面地概述微阵列数据并生成新的基因分类。截至2001年3月20日,yMGV数据库包含600万个测量值,代表了来自39篇微阵列出版物中932个实验的全基因组表达比较。yMGV界面可在http://transcriptome.ens.fr/ymgv/获取。