Goldman L R, Shannon M W
Pediatrics. 2001 Jul;108(1):197-205. doi: 10.1542/peds.108.1.197.
Mercury is a ubiquitous environmental toxin that causes a wide range of adverse health effects in humans. Three forms of mercury (elemental, inorganic, and organic) exist, and each has its own profile of toxicity. Exposure to mercury typically occurs by inhalation or ingestion. Readily absorbed after its inhalation, mercury can be an indoor air pollutant, for example, after spills of elemental mercury in the home; however, industry emissions with resulting ambient air pollution remain the most important source of inhaled mercury. Because fresh-water and ocean fish may contain large amounts of mercury, children and pregnant women can have significant exposure if they consume excessive amounts of fish. The developing fetus and young children are thought to be disproportionately affected by mercury exposure, because many aspects of development, particularly brain maturation, can be disturbed by the presence of mercury. Minimizing mercury exposure is, therefore, essential to optimal child health. This review provides pediatricians with current information on mercury, including environmental sources, toxicity, and treatment and prevention of mercury exposure.
汞是一种普遍存在的环境毒素,会对人类健康造成广泛的不良影响。汞有三种形式(元素汞、无机汞和有机汞),每种形式都有其自身的毒性特征。汞的暴露通常通过吸入或摄入发生。吸入后很容易被吸收,汞可能成为室内空气污染物,例如,家中元素汞泄漏后;然而,工业排放导致的环境空气污染仍然是吸入汞的最重要来源。由于淡水鱼和海鱼可能含有大量汞,如果儿童和孕妇食用过量的鱼,就可能受到大量汞暴露。发育中的胎儿和幼儿被认为受汞暴露的影响尤为严重,因为发育的许多方面,特别是大脑成熟,会因汞的存在而受到干扰。因此,尽量减少汞暴露对于儿童的最佳健康至关重要。本综述为儿科医生提供了有关汞的最新信息,包括环境来源、毒性以及汞暴露的治疗和预防。