Trenkwalder C, Wetter T C, Stiasny K, Clarenbach P
Georg-August-Universität Göttingen, Abteilung Klinische Neurophysiologie, Robert-Koch-Str. 40, 37075 Göttingen.
Nervenarzt. 2001 Jun;72(6):425-36. doi: 10.1007/s001150050774.
Restless legs syndrome is one of the most common neurological disorders, with a prevalence of 2% to 9% in the elderly population. Sensory and motor symptoms of the legs and an urge to move that occur at rest may lead to severe sleep disturbances and are part of the syndrome. Typical history and normal neurological examination lead to the clinical diagnosis. Additional laboratory and neurophysiological investigations are necessary to rule out associated diseases. The indication for polysomnography to record periodic limb movements in sleep must be discussed in individual cases. Treatment strategies will be recommended individually according to the disease severity. In this article we present an overview of the clinical symptomatology and include recommendations on diagnosis and treatment of RLS and differentiation of RLS from periodic limb movement disorder. To this purpose, the Motor System and Sleep Work Group of the German Society of Sleep Medicine presents modified guidelines for diagnosis and treatment of RLS according to recent recommendations of the American Sleep Disorder Association.
不宁腿综合征是最常见的神经系统疾病之一，在老年人群中的患病率为2%至9%。腿部的感觉和运动症状以及休息时出现的活动冲动可能导致严重的睡眠障碍，这是该综合征的一部分。典型的病史和正常的神经系统检查可得出临床诊断。需要进行额外的实验室和神经生理学检查以排除相关疾病。对于记录睡眠中周期性肢体运动的多导睡眠图检查的指征，必须在个别病例中进行讨论。治疗策略将根据疾病严重程度单独推荐。在本文中，我们概述了临床症状，并包括关于不宁腿综合征的诊断和治疗以及不宁腿综合征与周期性肢体运动障碍鉴别的建议。为此，德国睡眠医学协会运动系统与睡眠工作组根据美国睡眠障碍协会的最新建议，提出了不宁腿综合征诊断和治疗的修订指南。
