Cerebellar atrophy in an epileptic child: is it due to phenytoin?
作者信息
Ahuja S R, Karande S, Kulkarni M V
机构信息
Division of Paediatric Neurology, Department of Paediatrics, LTM Medical College and Hospital, Sion, Mumbai - 400 022, India.
出版信息
J Postgrad Med. 2000 Oct-Dec;46(4):278-9.
PMID:11435657
Abstract
A four and half year old epileptic child on phenytoin therapy since one year presented with signs of cerebellar dysfunction. Serum phenytoin level was high (33 mcg/ml) and computerised tomographic scan of the brain showed severe generalised cerebellar atrophy. The cerebellar signs represented drug over dosage and toxicity and persisted long after omission of phenytoin.
摘要
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Cerebellar atrophy in an epileptic child: is it due to phenytoin?
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