Cerebellar atrophy in an epileptic child: is it due to phenytoin?
作者信息
Ahuja S R, Karande S, Kulkarni M V
机构信息
Division of Paediatric Neurology, Department of Paediatrics, LTM Medical College and Hospital, Sion, Mumbai - 400 022, India.
出版信息
J Postgrad Med. 2000 Oct-Dec;46(4):278-9.
PMID:11435657
Abstract
A four and half year old epileptic child on phenytoin therapy since one year presented with signs of cerebellar dysfunction. Serum phenytoin level was high (33 mcg/ml) and computerised tomographic scan of the brain showed severe generalised cerebellar atrophy. The cerebellar signs represented drug over dosage and toxicity and persisted long after omission of phenytoin.
摘要
Zotero 插件