Rossi M, Furrer H
Ambulatorium für Infektionskrankheiten und Reisemedizin, Inselspital Bern.
Ther Umsch. 2001 Jun;58(6):381-6. doi: 10.1024/0040-5930.58.6.381.
Many HIV-infected persons travel from temperate zones to (sub)tropical destinations. HIV-specific immigration issues, medical resources abroad and problems regarding travelling with multiple medications have to be anticipated. When prescribing immunizations and specific chemoprophylaxis, the stage of immunodeficiency as well as drug interactions with antiretrovirals and medicaments against opportunistic infections have to be taken into account. Live vaccines may be contraindicated. Immunocompromised HIV-infected travellers have a higher risk for serious courses of diseases by enteropathogens. Therefore a good information about food hygiene is important and a prescription of an antibiotic to take in case of severe diarrhea may be indicated. A new antiretroviral combination therapy should not be started immediately before travelling to the tropics. The possibility to continue an established HIV treatment during travel has to be evaluated cautiously. With good pre-travel advice the risk of severe health problems is low for most HIV-infected travellers.
许多艾滋病毒感染者从温带地区前往(亚)热带目的地。必须预见到与艾滋病毒相关的移民问题、国外的医疗资源以及携带多种药物旅行的问题。在开具免疫接种和特定化学预防药物时,必须考虑免疫缺陷的阶段以及与抗逆转录病毒药物和预防机会性感染药物的药物相互作用。活疫苗可能是禁忌的。免疫功能低下的艾滋病毒感染旅行者感染肠道病原体导致疾病严重发作的风险更高。因此,了解良好的食品卫生知识很重要,可能需要开具抗生素处方以便在严重腹泻时服用。在前往热带地区之前不应立即开始新的抗逆转录病毒联合治疗。必须谨慎评估在旅行期间继续既定艾滋病毒治疗的可能性。通过良好的旅行前建议,大多数艾滋病毒感染旅行者出现严重健康问题的风险较低。