Oostenbrink J B, Rutten-van Mölken M P, Sluyter-Opdenoordt T S
Institute for Medical Technology Assessment, Erasmus University Rotterdam, The Netherlands.
J Glaucoma. 2001 Jun;10(3):184-91. doi: 10.1097/00061198-200106000-00007.
To estimate resource use and costs associated with the diagnosis and treatment of glaucoma and ocular hypertension in the Netherlands in 1996 and to determine how costs differed between patients, diagnoses, and hospitals.
Patient characteristics and glaucoma-related resource use were collected for 500 patients with glaucoma or ocular hypertension from the medical records of 10 hospitals. Costs were calculated by multiplying the health care resource use of each patient with actual unit costs. Multiple least-squares regression was used to analyze the relationship between costs and patient characteristics, diagnosis, and type of hospital (general or academic).
The mean annual frequency of visits to the ophthalmologist for patients with ocular hypertension and glaucoma was 2.43 and 3.74, respectively, and the mean cost per patient was $280 and $559, respectively. The mean cost of patients with glaucoma who had no changes in medication therapy was $347 and increased to $1,765 in patients with more than three adjustments in medication therapy. Outpatient visits to the ophthalmologist and medication contributed most to total costs. Regression analysis showed that costs were significantly related to intraocular pressure, diagnosis, severe excavation of the optic nerve head, and type of hospital.
The costs of patients with glaucoma were twice as high as the costs of patients with ocular hypertension. Aside from diagnosis, differences in costs between patients could partly be explained by baseline patient characteristics. Patients in academic hospitals had more severe glaucoma and treatment was considerably more expensive than for patients in nonacademic hospitals.
评估1996年荷兰青光眼和高眼压症诊断与治疗的资源使用情况及相关成本,并确定患者、诊断及医院之间的成本差异。
从10家医院的病历中收集了500例青光眼或高眼压症患者的特征及青光眼相关资源使用情况。通过将每位患者的医疗资源使用量乘以实际单位成本来计算成本。采用多元最小二乘法回归分析成本与患者特征、诊断及医院类型(综合医院或学术医院)之间的关系。
高眼压症和青光眼患者每年平均看眼科医生的次数分别为2.43次和3.74次,每位患者的平均成本分别为280美元和559美元。药物治疗无变化的青光眼患者平均成本为347美元,药物治疗调整超过三次的患者平均成本增至1765美元。门诊看眼科医生和药物费用占总成本的比例最大。回归分析表明,成本与眼压、诊断、视神经乳头严重凹陷及医院类型显著相关。
青光眼患者的成本是高眼压症患者的两倍。除诊断外,患者之间的成本差异部分可由患者基线特征解释。学术医院的患者青光眼病情更严重,治疗费用比非学术医院的患者高得多。