Denis Philippe, Lafuma Antoine, Berdeaux Gilles
Hôpital Edouard Herriot, Service d'ophtalmologie, Lyon, France.
J Glaucoma. 2004 Aug;13(4):283-90. doi: 10.1097/00061198-200408000-00005.
To describe the patterns and the economics of glaucoma treatment.
Ophthalmologists selected at random were asked to include 4 consecutive patients over 18 years of age seen in consultation during a week. Socio-demographics, general and eye comorbidities, glaucoma risk factors, clinical data, and medical item consumption data for the preceding 5 years were collected for each patient. The economic perspective was societal, and predictive medical factors of costs were identified using a stepwise regression.
Eighty-eight ophthalmologists included 337 patients, with a gender ratio of 4 males to 6 females, and a mean age of 62. Thirty-four percent had OHT. Glaucoma patients were older and no difference was found on the known confounding factors. Patients with glaucoma visited practitioners more often than those with OHT, had more exams, more often used expensive drug combination therapies, and had more hospitalizations. Drugs represented 37.1% to 63.1% of the expenses followed by exams (17.7% to 34.3%) and visits (13.8% to 28.0%). Two clinical factors contributed to costs: abnormalities of the optic nerve head the day of the study visit and the number of treatment changes. These were followed by intraocular pressure (IOP) and visual acuity.
Two major independent factors explained the bulk of total cost variance: drug treatment changes and the presence of glaucoma instead of OHT. They contributed independently in an additive way to total cost.
描述青光眼治疗的模式及经济学情况。
随机选取眼科医生,要求其纳入一周内会诊的4例18岁以上的连续患者。收集每位患者的社会人口统计学信息、全身及眼部合并症、青光眼危险因素、临床数据以及前5年的医疗项目消费数据。从社会角度进行经济学分析,并采用逐步回归法确定成本的预测医学因素。
88名眼科医生纳入了337例患者,男女比例为4:6,平均年龄为62岁。34%的患者患有高眼压症。青光眼患者年龄更大,在已知的混杂因素方面未发现差异。青光眼患者比高眼压症患者看医生更频繁,检查更多,更常使用昂贵的联合药物治疗,住院次数也更多。药物费用占总费用的37.1%至63.1%,其次是检查费用(17.7%至34.3%)和就诊费用(13.8%至28.0%)。两个临床因素导致了成本增加:研究就诊当天视神经乳头异常以及治疗方案改变的次数。其次是眼压和视力。
两个主要独立因素解释了总成本差异的大部分:药物治疗方案改变以及患有青光眼而非高眼压症。它们以累加的方式独立地对总成本产生影响。