• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

紧密连接的分子结构及其在上皮运输中的作用。

Molecular structure of tight junctions and their role in epithelial transport.

作者信息

Anderson J M

机构信息

Yale School of Medicine, New Haven, Connecticut 06520-8019, USA.

出版信息

News Physiol Sci. 2001 Jun;16:126-30. doi: 10.1152/physiologyonline.2001.16.3.126.

DOI:10.1152/physiologyonline.2001.16.3.126
PMID:11443232
Abstract

Tight junctions create a paracellular barrier with physiological properties that differ among epithelia. Among these differences are electrical resistance and discrimination for solute size and charge. Emerging evidence suggests that a large family of transmembrane proteins called the claudins create these variable properties.

摘要

紧密连接形成了一种细胞旁屏障，其生理特性在不同上皮组织中存在差异。这些差异包括电阻以及对溶质大小和电荷的辨别能力。新出现的证据表明，一大类被称为claudin的跨膜蛋白造就了这些可变特性。

相似文献

1
Molecular structure of tight junctions and their role in epithelial transport.紧密连接的分子结构及其在上皮运输中的作用。
News Physiol Sci. 2001 Jun;16:126-30. doi: 10.1152/physiologyonline.2001.16.3.126.
2
Tight junctions: closing in on the seal.
Curr Biol. 1999;9(24):R922-4. doi: 10.1016/s0960-9822(00)80105-0.
3
Identification of MarvelD3 as a tight junction-associated transmembrane protein of the occludin family.鉴定MarvelD3为闭合蛋白家族中与紧密连接相关的跨膜蛋白。
BMC Cell Biol. 2009 Dec 22;10:95. doi: 10.1186/1471-2121-10-95.
4
Claudins and epithelial paracellular transport.紧密连接蛋白与上皮细胞旁转运
Annu Rev Physiol. 2006;68:403-29. doi: 10.1146/annurev.physiol.68.040104.131404.
5
[Claudins as tight junction proteins: the molecular element of paracellular transport].[作为紧密连接蛋白的克劳丁：细胞旁转运的分子元件]
Ross Fiziol Zh Im I M Sechenova. 2013 Feb;99(2):175-95.
6
The role of claudins in determining paracellular charge selectivity.紧密连接蛋白在决定细胞旁电荷选择性中的作用。
Proc Am Thorac Soc. 2004;1(1):38-41. doi: 10.1513/pats.2306013.
7
The structure and function of claudins, cell adhesion molecules at tight junctions.紧密连接中的细胞黏附分子——闭合蛋白的结构与功能
Ann N Y Acad Sci. 2000;915:129-35. doi: 10.1111/j.1749-6632.2000.tb05235.x.
8
Transmembrane proteins in the tight junction barrier.紧密连接屏障中的跨膜蛋白。
J Am Soc Nephrol. 1999 Jun;10(6):1337-45. doi: 10.1681/ASN.V1061337.
9
The Claudins: From Tight Junctions to Biological Systems.紧密连接蛋白 Claudin：从紧密连接到生物系统。
Trends Biochem Sci. 2019 Feb;44(2):141-152. doi: 10.1016/j.tibs.2018.09.008. Epub 2018 Oct 25.
10
Focus on "Claudins create charge-selective channels in the paracellular pathway between epithelial cells".
Am J Physiol Cell Physiol. 2002 Jul;283(1):C29-30. doi: 10.1152/ajpcell.00128.2002.

引用本文的文献

1
Ion and water permeation through claudin-10b and claudin-15 paracellular channels.离子和水通过claudin-10b和claudin-15细胞旁通道的渗透。
Comput Struct Biotechnol J. 2024 Nov 13;23:4177-4191. doi: 10.1016/j.csbj.2024.11.025. eCollection 2024 Dec.
2
In vitro analysis of antiviral immune response against avian influenza virus in chicken tracheal epithelial cells.鸡气管上皮细胞中抗禽流感病毒的抗病毒免疫反应的体外分析
Anim Biosci. 2024 Nov;37(12):2009-2020. doi: 10.5713/ab.24.0117. Epub 2024 Aug 22.
3
Experimental Inoculation of and and Its Impact on Alveolar Bone Loss and Oral and Gut Microbiomes.
和及其对牙槽骨丢失和口腔及肠道微生物组的影响的实验接种。
Int J Mol Sci. 2024 Jul 25;25(15):8090. doi: 10.3390/ijms25158090.
4
Biophysics of claudin proteins in tight junction architecture: Three decades of progress.紧密连接结构中 Claudin 蛋白的生物物理学：三十年的进展。
Biophys J. 2024 Aug 20;123(16):2363-2378. doi: 10.1016/j.bpj.2024.06.010. Epub 2024 Jun 10.
5
Effect of supplementing a Bacillus subtilis-based probiotic on performance, intestinal integrity, and serum antioxidant capacity and metabolites concentrations of heat-stressed growing pigs.枯草芽孢杆菌益生菌对热应激生长猪生产性能、肠道完整性和血清抗氧化能力及代谢产物浓度的影响。
J Anim Sci. 2024 Jan 3;102. doi: 10.1093/jas/skae012.
6
Evaluation of the Epithelial Barrier Integrity in Primary Cultures of Pig Mammary Epithelial Cells.猪乳腺上皮细胞原代培养中上皮屏障完整性的评价。
Methods Mol Biol. 2024;2749:151-164. doi: 10.1007/978-1-0716-3609-1_14.
7
Lower vitamin D levels are associated with the pathogenesis of inflammatory bowel diseases.维生素 D 水平较低与炎症性肠病的发病机制有关。
Medicine (Baltimore). 2023 Oct 13;102(41):e35505. doi: 10.1097/MD.0000000000035505.
8
Protective role of CFTR during fungal infection of cystic fibrosis bronchial epithelial cells with .CFTR 在囊性纤维化支气管上皮细胞真菌感染中的保护作用。
Front Cell Infect Microbiol. 2023 Aug 23;13:1196581. doi: 10.3389/fcimb.2023.1196581. eCollection 2023.
9
Curcumin Alleviates Singapore Grouper Iridovirus-Induced Intestine Injury in Orange-Spotted Grouper ().姜黄素减轻新加坡石斑鱼虹彩病毒诱导的点带石斑鱼肠道损伤（）。
Antioxidants (Basel). 2023 Aug 9;12(8):1584. doi: 10.3390/antiox12081584.
10
Tight Junction Protein Signaling and Cancer Biology.紧密连接蛋白信号与癌症生物学。
Cells. 2023 Jan 6;12(2):243. doi: 10.3390/cells12020243.