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[皮肤密度测定法在绝经前后女性脊柱骨量减少诊断中的价值]

[The value of skin densitometry in diagnosis of decreased bone mass in the spine of women during the period around and post-menopause].

作者信息

Szymula J, Mielnik J, Szałkiewicz J, Szczurowicz A, Lech M

机构信息

I Kliniki Połoznictwa i Ginekologii Instytutu Połoznictwa i Chorób Kobiecych AM w Gdańsku.

出版信息

Ginekol Pol. 2001 Apr;72(4):236-40.

Abstract

OBJECTIVE

In peri- and postmenopausal women, the association of skin thickness with bone mass is well described, and a low skin thickness is a useful predictor of osteoporosis. In this study the association between skin thickness and bone mass of lumbar spine in peri- and postmenopausal women was assessed; and the potential for skin thickness as a screening test for osteoporosis evaluated.

DESIGN/METHODS: Skin thickness was measured at the arm by ultrasonography (probe 22 MHz). Bone mass was measured at lumbar spine by dual-energy X-ray absorptiometry. One hundred and three peri- and postmenopausal women were studied.

RESULT

Successive decrease of skin thickness going along with the loss of lumbar spine bone mass was found. There was a statistically significant difference (p < 0.05) in skin thickness between group of females with normal bone mass and group with osteoporosis.

CONCLUSIONS

Ultrasound skin measurement is a very simple method which can be used in the diagnostics of osteoporosis of the lumbar spine in peri- and postmenopausal women.

摘要

目的

在围绝经期和绝经后女性中,皮肤厚度与骨量之间的关联已有充分描述,皮肤厚度低是骨质疏松症的一个有用预测指标。本研究评估了围绝经期和绝经后女性皮肤厚度与腰椎骨量之间的关联,并评估了皮肤厚度作为骨质疏松症筛查试验的潜力。

设计/方法:通过超声(22MHz探头)测量手臂处的皮肤厚度。通过双能X线吸收法测量腰椎的骨量。对103名围绝经期和绝经后女性进行了研究。

结果

发现随着腰椎骨量的丢失,皮肤厚度连续下降。骨量正常的女性组与骨质疏松症女性组之间的皮肤厚度存在统计学显著差异(p<0.05)。

结论

超声测量皮肤厚度是一种非常简单的方法,可用于诊断围绝经期和绝经后女性的腰椎骨质疏松症。

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