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Thienyl acrylamides and thienyl pyrazolines as potential schistosomicidal agents.

作者信息

El-kerdawy M M, Samour A A, El-agamey A A

出版信息

Pharmazie. 1975 Feb;30(2):76-7. doi: 10.1002/chin.197522257.

DOI:10.1002/chin.197522257
PMID:1144504
Abstract

Alpha-Thienyl-N-substituted acrylamides that possess analogous structures to known schistosomicidal agents were synthesized. Two chalcones were prepared by condensing alpha-thiophenealdehyde and acetophenone or its o-hydroxy derivative. Cyclization of the chalcones with hydrazine hydrate or monosubstituted hydrazines afforded 1.3.5 trisubstituted 2-pyrazoline

摘要

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