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2型单纯疱疹病毒:急性视网膜坏死综合征的一个病因。

Herpes simplex virus type 2: a cause of acute retinal necrosis syndrome.

作者信息

Markomichelakis N N, Zafirakis P, Karambogia-Karefillidi P, Drakoulis N, Vagiakou-Boudri E, Paterakis G, Apostolopoulos M

机构信息

Department of Ophthalmology, General Hospital of Athens, Athens Medical School, Athens, Greece.

出版信息

Ocul Immunol Inflamm. 2001 Jun;9(2):103-9. doi: 10.1076/ocii.9.2.103.3974.

Abstract

PURPOSE

To describe a case of herpes simplex virus type 2 (HSV-2) acute retinal necrosis syndrome (ARN) in a 13-year-old immunocompetent girl.

METHODS

Polymerase chain reaction (PCR), cultures, flow cytometry, and cytology were performed on the vitreous sample.

RESULTS

Both PCR studies and vitreous cultures revealed HSV-2 as the cause of ARN. Flow cytometry showed CD4+, CD8+, and natural killer cells. The visual outcome of the patient was 20/200.

CONCLUSION

Successful culture of HSV-2 from the vitreous specimen in a patient with ARN proved HSV-2 to be one of the causes of ARN. The successful culture of HSV-2 has not been previously reported.

摘要

目的

描述一名13岁免疫功能正常女孩的2型单纯疱疹病毒(HSV - 2)急性视网膜坏死综合征(ARN)病例。

方法

对玻璃体样本进行聚合酶链反应(PCR)、培养、流式细胞术和细胞学检查。

结果

PCR研究和玻璃体培养均显示HSV - 2是ARN的病因。流式细胞术显示有CD4 +、CD8 +和自然杀伤细胞。患者的视力结果为20/200。

结论

在一名ARN患者的玻璃体标本中成功培养出HSV - 2,证明HSV - 2是ARN的病因之一。此前尚未报道过成功培养出HSV - 2的情况。

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