[一种评估亚硝酸盐对血液脱氧动力学影响的新型实验方法]
[A novel experimental method for evaluation of effect of nitrites on blood deoxygenation kinetics].
作者信息
Terovskiĭ V B, Shumilova T E
机构信息
Research Center for Ecological Safety, Russian Academy of Sciences, St. Petersburg, Russia.
出版信息
Biofizika. 2001 May-Jun;46(3):541-4.
PMID:11449558
Abstract
A new method for studying the oxygen-binding properties of blood is proposed, which is based on the analysis of transient processes on oxygen electrodes. The method was used to study the effect of sodium nitrite on the kinetics of dissociation of oxyhemoglobin in rat blood. It was shown that the rate of oxygen transport decreases at nitrite concentrations 1-5 mg/100 g body weight.
摘要
提出了一种基于对氧电极瞬态过程分析来研究血液氧结合特性的新方法。该方法用于研究亚硝酸钠对大鼠血液中氧合血红蛋白解离动力学的影响。结果表明，当亚硝酸钠浓度为1 - 5毫克/100克体重时，氧运输速率降低。
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