Rubin S O
Scand J Urol Nephrol. 1975;9(2):94-9. doi: 10.3109/00365597509180913.
Fourteen personal cases of agenesia of the vas deferens, bilateral in 12 and unilateral in 2, are described. In 13 of the cases the diagnosis was confirmed by surgical exploration. In most of the cases cytologic examination of aspiration biopsy specimens and histologic examination of surgical specimens of the testes showed that spermatogenesis was normal. The appearance of biopsy specimens of the epididymides were normal except for a certain degree of interstitital fibrosis and dilation of the ductus epididymidis. Endeavours to produce an artificial spermatocele with the aid of an isolated flap of tunica vaginalis in several patients proved unsuccessful. In one patient with a naturally preformed spermatocele the latter was aspirated, and the patient's wife was inseminated with the cellular content from the aspirate. This procedure has been repeated on several occasions, but so far without any subsequent conception. The failure of treatment of these patients may perhaps be due to some change in the function of their epididymides. This possibility is discussed.
本文描述了14例输精管缺如的个人病例，其中12例为双侧缺如，2例为单侧缺如。13例病例经手术探查确诊。大多数病例中，睾丸穿刺活检标本的细胞学检查和手术标本的组织学检查显示生精功能正常。除了一定程度的间质纤维化和附睾管扩张外，附睾活检标本外观正常。在几名患者中，试图借助孤立的鞘膜瓣制作人工精液囊肿，但均未成功。在一名自然形成精液囊肿的患者中，抽取了囊肿内容物，并将其注入患者妻子体内。该过程已重复多次，但迄今为止尚无后续受孕情况。这些患者治疗失败可能是由于附睾功能发生了某些变化。对此可能性进行了讨论。
