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斯堪的纳维亚地区关于激素替代疗法的知识、态度及管理策略:丹麦、挪威和瑞典妇科医生的比较

Knowledge, attitudes and management strategies in Scandinavia concerning hormone replacement therapy: a comparison between gynecologists in Denmark, Norway and Sweden.

作者信息

Nilsen S T, Pedersen A T, Moen M H, Milsom I, Mattsson L A, Iversen O E, Larsen P M, Andersson K

机构信息

Department of Obstetrics and Gynecology, Haukeland University Hospital, N-5021 Bergen, Norway.

出版信息

Maturitas. 2001 Jul 25;39(1):83-90. doi: 10.1016/s0378-5122(01)00187-6.

Abstract

OBJECTIVES

To describe and compare attitudes, knowledge and management strategies concerning the prescription of hormone replacement therapy (HRT) between gynecologists from three Scandinavian countries.

DESIGN AND METHODS

In a cross-sectional study gynecologists in Denmark (n=386), Norway (n=475) and Sweden (n=1323) were invited by letter to complete and return an enclosed questionnaire. Then 1653 of the 2184 (76%) contacted gynecologists completed and returned the questionnaire.

RESULTS

of the 1653 Scandinavian gynecologists, 42% offered HRT to all women provided there was no contraindication, while 58% recommended HRT to selected women after considering the advantages and disadvantages of HRT. In Norway and Sweden, the proportion of gynecologists routinely prescribing HRT for women without contraindications increased with age and in the oldest age group of gynecologists (>55 years) 49 and 56%, respectively, recommended HRT to all women. The gynecologists were unanimous in their choice of the type of HRT for perimenopausal women as 94% preferred cyclical or sequential combined (estrogen/progestogen) treatment or estrogen monotherapy (orally or transdermally) for hysterectomized women (95%). For postmenopausal women, 75% of the gynecologists offered continuous combined HRT while cyclical combined therapy was chosen by 15% of the gynecologists. No significant differences were found between physicians in the three countries regarding indications and contraindications to HRT.

CONCLUSIONS

Scandinavian gynecologists are generally well informed concerning HRT and liberally recommend HRT for women without contraindications.

摘要

目的

描述并比较来自三个斯堪的纳维亚国家的妇科医生在激素替代疗法(HRT)处方方面的态度、知识和管理策略。

设计与方法

在一项横断面研究中,通过信函邀请丹麦(n = 386)、挪威(n = 475)和瑞典(n = 1323)的妇科医生填写并返还随附的问卷。在联系的2184名妇科医生中,有1653名(76%)完成并返还了问卷。

结果

在1653名斯堪的纳维亚妇科医生中,42%的医生在无禁忌证的情况下会为所有女性提供HRT,而58%的医生在考虑HRT的利弊后会向部分女性推荐HRT。在挪威和瑞典,无禁忌证的女性中常规开具HRT的妇科医生比例随年龄增长而增加,在年龄最大的妇科医生组(>55岁)中,分别有49%和56%的医生会向所有女性推荐HRT。妇科医生在围绝经期女性HRT类型的选择上意见一致,94%的医生倾向于为子宫切除的女性选择周期性或序贯联合(雌激素/孕激素)治疗或雌激素单一疗法(口服或经皮)(95%)。对于绝经后女性,75%的妇科医生提供连续联合HRT,15%的妇科医生选择周期性联合疗法。在这三个国家的医生中,关于HRT的适应证和禁忌证未发现显著差异。

结论

斯堪的纳维亚的妇科医生通常对HRT有充分了解,并会为无禁忌证的女性广泛推荐HRT。

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