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[一例酷似垂体腺瘤的鞍内脑膜瘤病例]

[A case of intrasellar meningioma mimicking pituitary adenoma].

作者信息

Matsumoto S, Hayase M, Imamura H, Oda Y, Kikuchi H, Katayama M, Ishihara T

机构信息

Department of Neurosurgery, Kobe City General Hospital, 4-6 Minatojima-naka-machi, Chuo-ku, Kobe 650-0046, Japan.

出版信息

No Shinkei Geka. 2001 Jun;29(6):551-7.

Abstract

The authors report a patient with a rare intrasellar meningioma mimicking pituitary adenoma. A 60-year-old man was admitted to our hospital for evaluation of general fatigue. He had no neurological deficit including visual function. Endocrinological tests revealed panhypopituitarism. The craniogram showed slight enlargement of the sella turcica with thinning of the dorsum sellae. CT scan and MR imaging demonstrated a homogeneously enhanced intrasellar mass with slight suprasellar extension. Partial removal of the mass was performed via the transsphenoidal approach because it was extremely firm and hemorrhagic. Histological diagnosis was transitional meningioma. The patient has been well for two years after surgery without tumor progression on MR imaging. It is mandatory to distinguish intrasellar meningioma from pituitary adenoma preoperatively because of marked difference in their treatment strategies. Despite recent advances in neurodiagnostic imaging, it may still be difficult to differentiate pituitary adenoma from intrasellar meningioma. When we re-evaluated the MR imaging, we recognized that the tumor had demonstrated specific findings, ruling out pituitary adenoma, namely bright and homogeneous enhancement, dense enhancement in the early phase on the dynamic MR study, and flow void signal within the mass. The authors emphasize that careful evaluations of MR imaging will allow the correct preoperative diagnosis in patients with intrasellar meningioma mimicking pituitary macroadenoma.

摘要

作者报告了一例罕见的鞍内脑膜瘤,临床表现酷似垂体腺瘤。一名60岁男性因全身乏力入院。他没有包括视觉功能在内的神经功能缺损。内分泌检查显示全垂体功能减退。颅骨平片显示蝶鞍轻度扩大,鞍背变薄。CT扫描和磁共振成像显示鞍内肿块均匀强化,并有轻度鞍上延伸。由于肿块质地极硬且有出血,遂经蝶窦入路进行了部分切除。组织学诊断为过渡型脑膜瘤。患者术后两年情况良好,磁共振成像显示无肿瘤进展。由于鞍内脑膜瘤和垂体腺瘤的治疗策略有显著差异,术前必须将两者区分开来。尽管神经诊断成像技术最近有所进展,但区分垂体腺瘤和鞍内脑膜瘤可能仍然困难。当我们重新评估磁共振成像时,我们发现该肿瘤具有一些特定表现,可排除垂体腺瘤,即均匀明亮强化、动态磁共振研究早期的密集强化以及肿块内的流空信号。作者强调,仔细评估磁共振成像将有助于对酷似垂体大腺瘤的鞍内脑膜瘤患者进行正确的术前诊断。

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