Neri G, Zanco P, Buchberger R
Department of Cardiology, ULSS 8 Veneto, Castelfranco Veneto, Italy.
Ital Heart J. 2001 Jun;2(6):472-4.
The effects of biventricular pacing on myocardial wall function are well known, but, at the moment, its real effects on myocardial metabolism are unclear. In patients affected by left bundle branch block, at positron emission tomography a septal defect of the uptake of 18F-fluorodeoxyglucose (FDG) was referred. There were no alterations in myocardial perfusion, suggesting possible metabolic damage. In this paper we report the case of a patient affected by dilated cardiomyopathy and left bundle branch block treated with a biventricular device. Biventricular pacing resolved both the wall motion alterations as well as the defect in FDG uptake present in the septal area. On the contrary, during biventricular pacing there were no modifications in myocardial perfusion as compared to basal evaluation.
双心室起搏对心肌壁功能的影响是众所周知的，但目前其对心肌代谢的实际影响尚不清楚。在患有左束支传导阻滞的患者中，正电子发射断层扫描显示存在18F-氟脱氧葡萄糖（FDG）摄取的间隔缺损。心肌灌注没有改变，提示可能存在代谢损伤。在本文中，我们报告了一例扩张型心肌病合并左束支传导阻滞患者接受双心室装置治疗的病例。双心室起搏解决了室壁运动改变以及间隔区域存在的FDG摄取缺损。相反，与基础评估相比，双心室起搏期间心肌灌注没有改变。
