Doolke A, Cannerfelt R, Anderson R, Jakobsson J
Department of Anaesthesia, Sabbatsberg Hospital, S-113 24, Stockholm, Sweden
Ambul Surg. 2001 Jul;9(2):95-98. doi: 10.1016/s0966-6532(01)00101-9.
The potential for minimising anaesthetic gas consumption with a circle absorber system is related to fresh gas flow. This study measured the actual sevoflurane consumption during elective arthroscopy of the knee in 75 ASA I-II patients randomised to three fresh gas flow rates (6, 3, and 1.5 l/min) using sevoflurane and O(2):N(2)O (1:2) after intravenous induction with fentanyl and propofol. A circle absorber system was used with a laryngeal mask airway. Anaesthetic duration, discharge time and postoperative pain did not differ between groups. Sevoflurane consumption was more than doubled with each doubling of fresh gas flow (0.07+/-0.03; 0.16+/-0.05; 0.41+/-0.12 ml sevoflurane/min; for gas flow 1.5, 3, 6 l/min; P<0.01). The hourly sevoflurane related cost decreased from 15.5 to 2.8 US$ when reducing the fresh gas flow from 6 to 1.5 l/min. Decreasing the fresh gas flow from 6 to 1.5 l/min provides good anaesthetic depth with effective reduction in anaesthetic consumption, cost and environmental burden.
使用循环吸收系统将麻醉气体消耗量降至最低的可能性与新鲜气体流量有关。本研究测量了75例ASA I-II级患者在择期膝关节关节镜检查期间的实际七氟烷消耗量，这些患者在静脉注射芬太尼和丙泊酚后，随机分为三种新鲜气体流量（6、3和1.5升/分钟），使用七氟烷和O₂:N₂O（1:2）。使用带有喉罩气道的循环吸收系统。各组之间的麻醉持续时间、出院时间和术后疼痛没有差异。新鲜气体流量每增加一倍，七氟烷消耗量增加一倍以上（七氟烷消耗量分别为0.07±0.03；0.16±0.05；0.41±0.12毫升/分钟，对应气体流量为1.5、3、6升/分钟；P<0.01）。当新鲜气体流量从6升/分钟降至1.5升/分钟时，每小时七氟烷相关成本从15.5美元降至2.8美元。将新鲜气体流量从6升/分钟降至1.5升/分钟可提供良好的麻醉深度，同时有效降低麻醉剂消耗量、成本和环境负担。
