Binaghi S, Maeder P, Uské A, Meuwly J Y, Devuyst G, Meuli R A
Department of Radiology, University Hospital of Lausanne, CHUV, Rue du Bugnon, CH-1011 Lausanne, Switzerland.
Eur Neurol. 2001;46(1):25-34. doi: 10.1159/000050752.
To evaluate the role of computed tomography angiography (CTA) and magnetic resonance angiography (MRA) in the quantification of atherosclerotic stenosis of carotid artery bifurcation in comparison with digital substraction angiography (DSA) and Doppler sonography (DS).
Twenty-five patients with atherosclerotic disease of the carotid arteries with proven stenosis by DSA, had spiral CTA, MRA using two- and three-dimensional time-of-flight gradient echo techniques, and DS using Doppler flow signal recording (total 47 carotid artery bifurcations). The degree of stenosis was measured according to the North American Symptomatic Carotid Endarterectomy Trial criteria: total occlusion (100%), severe (70-99%), moderate (30-69%) and mild (0-29%). The degree of stenosis measured by CTA, MRA and DS was compared to DSA, used as the gold standard.
Ninety-seven percent of MRA measures were equivalent to DSA, and 3% were underestimated; 96% of CTA measures were equivalent to DSA, and 4% were underestimated; 77% of DS measures were equivalent to DSA, 21% were overestimated and 2% were underestimated.
CTA and MRA are equally accurate methods in quantifying the degree of carotid bifurcation stenosis.
与数字减影血管造影(DSA)和多普勒超声检查(DS)相比,评估计算机断层血管造影(CTA)和磁共振血管造影(MRA)在量化颈动脉分叉处动脉粥样硬化狭窄中的作用。
25例经DSA证实有颈动脉粥样硬化疾病并伴有狭窄的患者,接受了螺旋CTA、使用二维和三维时间飞跃梯度回波技术的MRA以及使用多普勒血流信号记录的DS检查(共47个颈动脉分叉处)。根据北美症状性颈动脉内膜切除术试验标准测量狭窄程度:完全闭塞(100%)、重度(70 - 99%)、中度(30 - 69%)和轻度(0 - 29%)。将CTA、MRA和DS测量的狭窄程度与作为金标准的DSA进行比较。
97%的MRA测量结果与DSA相当,3%被低估;96%的CTA测量结果与DSA相当,4%被低估;77%的DS测量结果与DSA相当,21%被高估,2%被低估。
CTA和MRA在量化颈动脉分叉狭窄程度方面是同样准确的方法。