非洲爪蟾Iroquois家族同源框基因Irx4和Irx5的发育表达

Developmental expression of the Xenopus Iroquois-family homeobox genes, Irx4 and Irx5.

作者信息

Garriock R J, Vokes S A, Small E M, Larson R, Krieg P A

机构信息

Department of Cell Biology and Anatomy, University of Arizona Health Sciences Center, P.O. Box 245044, 1501 N. Campbell Avenue, Tucson, AZ 85724, USA.

出版信息

Dev Genes Evol. 2001 May;211(5):257-60. doi: 10.1007/s004270100147.

DOI:10.1007/s004270100147

PMID:11455441

Abstract

We have isolated and characterized the developmental expression of the Xenopus Iroquois 4 (Irx4) and Iroquois 5 (Irx5) homeodomain transcription factors. Irx4 is expressed in a subset of cells in the neural retina and the developing hindbrain and also, specifically, in the ventricle of the heart. Xenopus Irx5 is expressed in the developing midbrain, hindbrain, neural tube, and also in the retina.

摘要

我们已经分离并鉴定了非洲爪蟾Iroquois 4（Irx4）和Iroquois 5（Irx5）同源域转录因子的发育表达情况。Irx4在神经视网膜和发育中的后脑的一部分细胞中表达，并且特别地，也在心脏的心室中表达。非洲爪蟾Irx5在发育中的中脑、后脑、神经管以及视网膜中表达。