格雷夫斯病一例中的晨发性粒细胞减少症。
Morning granulocytopenia in a case of Graves' disease.
作者信息
Nakamura S, Isaji M, Ishimori M
机构信息
Department of Internal Medicine, Gifu Red Cross Hospital, Japan.
出版信息
Endocr J. 2001 Apr;48(2):181-4. doi: 10.1507/endocrj.48.181.
A 65-year-old woman with Graves' disease presented marked diurnal changes in white blood cell (WBC) and granulocyte counts. Granulocyte count was low and sometimes decreased to 0.2-0.3 x 10(9)/l in the early morning and increased in the afternoon irrespective of her thyroid status. She did not develop sore throat or fever during the investigation period. The present study indicates that these unusual diurnal changes in WBC and granulocyte counts should be considered in the differential diagnosis of agranulocytosis in Graves' disease patients treated with an antithyroid drug.
一名65岁患有格雷夫斯病的女性，其白细胞（WBC）和粒细胞计数呈现出明显的昼夜变化。粒细胞计数在清晨较低，有时会降至0.2 - 0.3×10⁹/L，下午则会升高，与她的甲状腺状态无关。在调查期间，她没有出现喉咙痛或发烧的症状。本研究表明，在对接受抗甲状腺药物治疗的格雷夫斯病患者粒细胞缺乏症进行鉴别诊断时，应考虑白细胞和粒细胞计数这些不寻常的昼夜变化。
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