Podnar T, Martanovic P, Gavora P, Masura J
The Children's Cardiac Center, University Children's Hospital, Bratislava, Slovakia.
Catheter Cardiovasc Interv. 2001 Jul;53(3):386-91. doi: 10.1002/ccd.1187.
The aim of the study was to assess the morphology of secundum-type atrial septal defects (ASD) with a view to percutaneous closure using Amplatzer septal occluders (ASO). One hundred and ninety patients who underwent closure of isolated secundum-type ASD between September 1995 and January 2000 were included. The morphology of the defects was studied using transthoracic and transesophageal echocardiography. Patients with defects of suitable morphology and size underwent percutaneous closure using ASO. The remaining patients underwent surgical closure. Centrally placed defects were observed in 46 patients (24.2%). Morphological variations of secundum-type ASD were detected in 144 patients (75.8%). One hundred and fifty-one patients (79.5%) underwent percutaneous closure using ASO. Thirty-nine patients (20.5%) underwent surgical closure. Centrally placed defects, defects with deficient superior anterior rim, multiple defects, and perforated aneurysms of the interatrial septum are morphological variations of secundum-type ASD suitable for percutaneous closure using ASO. Cathet Cardiovasc Intervent 2001;53:386-391.
本研究的目的是评估继发孔型房间隔缺损（ASD）的形态，以便使用Amplatzer房间隔封堵器（ASO）进行经皮封堵。纳入了1995年9月至2000年1月期间接受孤立性继发孔型ASD封堵的190例患者。使用经胸和经食管超声心动图研究缺损的形态。具有合适形态和大小缺损的患者接受了使用ASO的经皮封堵。其余患者接受了手术封堵。46例患者（24.2%）观察到中央型缺损。144例患者（75.8%）检测到继发孔型ASD的形态变异。151例患者（79.5%）接受了使用ASO的经皮封堵。39例患者（20.5%）接受了手术封堵。中央型缺损、上缘前部缺损、多发缺损以及房间隔穿孔性动脉瘤是适合使用ASO进行经皮封堵的继发孔型ASD的形态变异。《心血管介入治疗杂志》2001年；53：386 - 391。
