Shamsuzzaman A S, Somers V K
Divisions of Hypertension and Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic and Mayo Foundation, 200 First Street SW, Rochester, MN 55905, USA.
Ann N Y Acad Sci. 2001 Jun;940:488-99. doi: 10.1111/j.1749-6632.2001.tb03700.x.
The reflex mechanisms and interactions described in this overview provide some explanation for the range of neural circulatory responses evident during changes in breathing. The effects described represent the integrated responses to activation of several reflex mechanisms, including peripheral and central chemoreflexes, arterial baroreflexes, pulmonary stretch receptors, and ventricular mechanoreceptors. These interactions occur on a dynamic basis and the transfer characteristics of any single interaction are, in all likelihood, also highly dynamic. Nevertheless, it is only by attempting to understand individual reflexes and their modulating influences that a more thorough understanding of the responses to complex phenomena such as hyperventilation, apnea, and obstructive sleep apnea can be better understood.
本综述中描述的反射机制及相互作用，为呼吸变化期间明显的一系列神经循环反应提供了一些解释。所描述的效应代表了对多种反射机制激活的综合反应，这些机制包括外周和中枢化学反射、动脉压力反射、肺牵张感受器和心室机械感受器。这些相互作用是动态发生的，而且任何单一相互作用的传递特性很可能也是高度动态的。然而，只有通过尝试理解个体反射及其调节影响，才能更好地全面理解对诸如过度通气、呼吸暂停和阻塞性睡眠呼吸暂停等复杂现象的反应。
