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Current status of ribozymes as gene therapy agents for cancer.

作者信息

Wright L, Kearney P

机构信息

Hematology Research Laboratory, St. Vincent's Hospital, 384 Victoria St., Darlinghurst, New South Wales, 2010 Australia.

出版信息

Cancer Invest. 2001;19(5):495-509. doi: 10.1081/cnv-100103848.

DOI:10.1081/cnv-100103848

PMID:11458817

Abstract

摘要

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Current status of ribozymes as gene therapy agents for cancer.

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Current status of ribozymes as gene therapy agents for cancer.

Cancer Invest. 2001;19(5):495-509. doi: 10.1081/cnv-100103848.

Non-viral delivery of ribozymes for cancer gene therapy.

Expert Opin Biol Ther. 2004 Nov;4(11):1749-55. doi: 10.1517/14712598.4.11.1749.

Application of preformed hammerhead ribozymes in the gene therapy of cancer (review).

Int J Mol Med. 1999 Apr;3(4):381-4. doi: 10.3892/ijmm.3.4.381.

Ribozyme gene therapy for cancer nears clinical trials.

Oncology (Williston Park). 1995 Nov;9(11):1180, 1182.

Ribozyme therapy: RNA enzymes to the rescue.

Yale J Biol Med. 2002 Jul-Aug;75(4):215-9.

Therapeutic applications of ribozymes.

Pharmacol Ther. 1995;68(2):247-67. doi: 10.1016/0163-7258(95)02008-x.

Ribozyme-mediated cancer gene therapy.

Int J Urol. 1997 Jul;4(4):329-37. doi: 10.1111/j.1442-2042.1997.tb00203.x.

Ribozyme gene therapy: applications for molecular medicine.

Trends Mol Med. 2001 May;7(5):221-8. doi: 10.1016/s1471-4914(01)01965-7.

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Science. 1993 Dec 3;262(5139):1512-4. doi: 10.1126/science.8248799.

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引用本文的文献

Therapeutic regulation of gene expression in the inner ear using RNA interference.

Adv Otorhinolaryngol. 2009;66:13-36. doi: 10.1159/000218205. Epub 2009 Jun 2.

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Ribozyme-mediated REV1 inhibition reduces the frequency of UV-induced mutations in the human HPRT gene.

Nucleic Acids Res. 2003 Sep 1;31(17):4981-8. doi: 10.1093/nar/gkg725.

Current status of ribozymes as gene therapy agents for cancer.

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