Munafò M, Rigotti N, Lancaster T, Stead L, Murphy M
ICRF General Practice Research Group, University of Oxford, Oxford OX3 7LF, UK.
Thorax. 2001 Aug;56(8):656-63. doi: 10.1136/thorax.56.8.656.
An admission to hospital provides an opportunity to help people stop smoking. Individuals may be more open to help at a time of perceived vulnerability, and may find it easier to quit in an environment where smoking is restricted or prohibited. Providing smoking cessation services during hospitalisation may help more people to attempt and sustain an attempt to quit. The purpose of this paper is to systematically review the effectiveness of interventions for smoking cessation in hospitalised patients.
We searched the Cochrane Tobacco Addiction Group register, CINAHL, and the Smoking and Health database for studies of interventions for smoking cessation in hospitalised patients. Randomised and quasi-randomised trials of behavioural, pharmacological, or multi-component interventions to help patients stop smoking conducted with hospitalised patients who were current smokers or recent quitters were included. Studies of patients admitted for psychiatric disorders or substance abuse, those that did not report abstinence rates, and those with follow up of less than 6 months were excluded. Two of the authors extracted data independently for each paper, with assistance from others.
Intensive intervention (inpatient contact plus follow up for at least 1 month) was associated with a significantly higher cessation rate compared with controls (Peto odds ratio (OR) 1.82, 95% CI 1.49 to 2.22). Any contact during hospitalisation followed by minimal follow up failed to detect a statistically significant effect on cessation rate, but did not rule out a 30% increase in smoking cessation (Peto OR 1.09, 95% CI 0.91 to 1.31). There was insufficient evidence to judge the effect of interventions delivered only during the hospital stay. Although the interventions increased quit rates irrespective of whether nicotine replacement therapy (NRT) was used, the results for NRT were compatible with other data indicating that it increases quit rates. There was no strong evidence that clinical diagnosis affected the likelihood of quitting.
High intensity behavioural interventions that include at least 1 month of follow up contact are effective in promoting smoking cessation in hospitalised patients.
住院为帮助人们戒烟提供了契机。个体在感到脆弱时可能更愿意接受帮助,并且可能发现在吸烟受限或被禁止的环境中更容易戒烟。住院期间提供戒烟服务可能有助于更多人尝试并维持戒烟努力。本文旨在系统评价针对住院患者的戒烟干预措施的有效性。
我们检索了Cochrane烟草成瘾小组登记册、CINAHL以及吸烟与健康数据库,以查找有关住院患者戒烟干预措施的研究。纳入了对当前吸烟者或近期戒烟者进行的行为、药物或多成分干预以帮助其戒烟的随机和半随机试验。排除了因精神疾病或药物滥用入院的患者、未报告戒烟率的研究以及随访时间少于6个月的研究。两位作者在其他人的协助下独立为每篇论文提取数据。
与对照组相比,强化干预(住院期间接触加至少1个月的随访)与显著更高的戒烟率相关(Peto比值比(OR)1.82,95%可信区间1.49至2.22)。住院期间的任何接触后进行最少的随访未能发现对戒烟率有统计学显著影响,但不排除戒烟率增加30%(Peto OR 1.09,95%可信区间0.91至1.31)。没有足够的证据来判断仅在住院期间实施的干预措施的效果。尽管无论是否使用尼古丁替代疗法(NRT),干预措施都提高了戒烟率,但NRT的结果与其他表明其可提高戒烟率的数据一致。没有有力的证据表明临床诊断会影响戒烟的可能性。
包括至少1个月随访接触的高强度行为干预措施在促进住院患者戒烟方面是有效的。