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[慢性血液透析患者中热量-蛋白质营养不良的患病率]

[Prevalence of calorie protein malnutrition among patients in chronic hemodialysis].

作者信息

Huidobro A, Velasco N, Rojas T

机构信息

MRC International Nutrition Group, Department of Epidemiology & Public Health, London School of Hygiene and Tropical Medicine 49-51 Bedford Square, London WC1B 3DP.

出版信息

Rev Med Chil. 2001 May;129(5):495-502.

PMID:11464530
Abstract

BACKGROUND

Malnutrition has been strongly associated with morbidity and mortality in hemodialysis patients. In the other hand, dialysis allows a nutritional improvement in patients with more than 12 months in dialysis.

AIM

To study the prevalence of malnutrition among patients in hemodialysis.

PATIENTS AND METHODS

We measured clinical, anthropometric and biochemical parameters of nutritional status in chronic hemodialysed patients. Results were related to individual time in dialysis. Patients with more and less than 12 months in dialysis were compared.

RESULTS

Twenty nine patients (18 male) aged 14 to 65 years old, were studied. Mean caloric intake was 23.8 Cal/Kg and protein intake was 0.7 g/Kg. Mean body mass index was 21.7 +/- 3.7 kg/m2 Thirty eight percent of patients had a body mass index of less than 20 kg/m2. Mean serum albumin was 4.1 +/- 0.7 g/L; mean prealbumin was 33.5 +/- 7.9 mg% and creatinine was 9.6 +/- 2.8 mg%. Serum cholesterol was 182 mg% and triacylglycerol 129 mg%. PCR was 42.2 +/- 18.8 and Kt/V was 1.45 +/- 0.3. We did not find a correlation between nutritional markers and time in dialysis or a difference in nutritional parameters between patients with less or more than 12 months in dialysis.

CONCLUSIONS

These patients in chronic dialysis have a high prevalence of caloric malnutrition, which may be due to a poor caloric intake. Protein malnutrition parameters were normal in most patients. The absence of abnormal lipid levels, common in chronic renal failure, is noticeable.

摘要

背景

营养不良与血液透析患者的发病率和死亡率密切相关。另一方面,透析可使透析超过12个月的患者营养状况得到改善。

目的

研究血液透析患者中营养不良的患病率。

患者与方法

我们测量了慢性血液透析患者营养状况的临床、人体测量和生化参数。结果与个体透析时间相关。比较了透析时间超过和少于12个月的患者。

结果

研究了29例年龄在14至65岁之间的患者(18例男性)。平均热量摄入为23.8千卡/千克,蛋白质摄入为0.7克/千克。平均体重指数为21.7±3.7千克/平方米。38%的患者体重指数低于20千克/平方米。平均血清白蛋白为4.1±0.7克/升;平均前白蛋白为33.5±7.9毫克%,肌酐为9.6±2.8毫克%。血清胆固醇为182毫克%,甘油三酯为129毫克%。PCR为42.2±18.8,Kt/V为1.45±0.3。我们未发现营养指标与透析时间之间存在相关性,也未发现透析时间少于或超过12个月的患者在营养参数上存在差异。

结论

这些慢性透析患者热量营养不良的患病率较高,这可能是由于热量摄入不足所致。大多数患者蛋白质营养不良参数正常。慢性肾衰竭常见的血脂异常未出现,这一点值得注意。

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