Bagneid M, Kamel M S, Shaker A
Am J Clin Pathol. 1975 Jun;63(6):921-6. doi: 10.1093/ajcp/63.6.921.
The nitroblue tetrazolium (NBT) test was carried out on blood from ten normal individuals and 20 schistosomal patients, ten of whom had hepatosplenomegaly and ten hepatosplenomegaly and ascites. The test revealed defective neutrophils in patients who had hepatosplenomegaly accompained by ascites. The phagocytic and bactericidal effects from five of each of the two groups of patients; results substantiated tose obtained by the NBT screening test. The NBT screening test thus proved useful in detecting acquired defective function of neutrophils in a helminthic parasitic disease that is accompanied by frequent bacterial infections.
对10名正常人和20名血吸虫病患者的血液进行了硝基蓝四氮唑（NBT）试验，其中20名患者中有10名患有肝脾肿大，另外10名既有肝脾肿大又有腹水。试验显示，既有肝脾肿大又伴有腹水的患者存在中性粒细胞功能缺陷。对两组患者各5名进行吞噬和杀菌作用检测；结果证实了NBT筛查试验的结果。因此，NBT筛查试验被证明可用于检测在伴有频繁细菌感染的蠕虫寄生虫病中获得性中性粒细胞功能缺陷。
