Wilk P, Karipineni R, Dreiling D A, Danese C
Am J Gastroenterol. 1975 May;63(5):400-3.
Eight dogs underwent intestinal lymphatic block. Once intestinal lymphedema was established, a segment was excluded from continuity for four months and then restored to continuity. The lymphedema decreased during exclusion and reappeared after restoration to continuity. The relationship of the changes seen in the intestine following lymphatic block and to the changes observed in the bowel in regional enteritis suggests a pathogenetic role for lymphatic blockage and explains the pseudobeneficial effects of by-pass as well as the prompt recrudescence of pathology which follows reconstruction procedures.
八只狗接受了肠淋巴管阻断术。一旦建立了肠淋巴水肿,将一段肠管中断连接四个月,然后恢复连接。在肠管中断连接期间淋巴水肿减轻,恢复连接后又重新出现。肠淋巴管阻断后肠道出现的变化与局限性肠炎中观察到的肠道变化之间的关系表明,淋巴管阻塞在发病机制中起作用,并解释了旁路手术的假性有益效果以及重建手术后病理状况迅速复发的原因。