Tanière P, Peysson P, Scoazec J Y
Service Central d'Anatomie et Cytologie Pathologiques, Hôpital Edouard Herriot, 3, place d'Arsonval, 69437 Lyon.
Ann Pathol. 2001 Jun;21(3):285-8.
Endoscopic mucosectomy is a newly developed endoscopic technique allowing the resection of large fragments of digestive mucosa. The main indications of this technique are the staging and/or the treatment of superficial lesions of esophagus, stomach and colon. Resections by endoscopic mucosectomy raise specific problems of macroscopic technique and histological analysis. For correct inclusion, fragments must be pinned under a rigid support by the endoscopist. Their lateral margins must be sampled independently. The fragment must be included in totality. The histological report must indicate the depth of the resection and its quality, particularly the status of lateral and deep margins. The main difficulties of the histological analysis are due to the frequent occurrence of coagulation artefacts, which may hamper a correct interpretation of the lesions, particularly along the lateral margins. The appropriate management of endoscopic mucosal resections requires a good collaboration between endoscopists and pathologists.
内镜下黏膜切除术是一种新开发的内镜技术，可用于切除大片消化黏膜。该技术的主要适应症是食管、胃和结肠浅表病变的分期和/或治疗。内镜下黏膜切除术会引发宏观技术和组织学分析方面的特定问题。为了正确包埋，内镜医师必须将组织碎片固定在坚硬的支撑物下。必须独立采集其外侧边缘的样本。组织碎片必须完整包埋。组织学报告必须注明切除的深度及其质量，尤其是外侧和深部边缘的情况。组织学分析的主要困难在于凝血假象频繁出现，这可能会妨碍对病变的正确解读，尤其是沿外侧边缘的病变。内镜下黏膜切除术的恰当管理需要内镜医师和病理学家之间密切合作。
