Caballero Plasencia A M, Sofos Kontoyannis S, Valenzuela Barranco M, Martín Ruiz J L, Casado Caballero F J, Guilarte López-Mañas J
Department of Medicine, School of Medicine, Granada, Spain.
Rev Esp Enferm Dig. 2000 Dec;92(12):781-92.
The prevalence of dyspepsia in the community is poorly known, because most studies have used samples that were not representative of the general population. This study was intended to determine the prevalence of dyspepsia in a random sample of the general population, and its epidemiologic and sociodemographic characteristics.
In this descriptive study we used a questionnaire administered during a personal interview to survey a random sample of 264 subjects in a Mediterranean population.
The prevalence of dyspepsia was 24%; we found no relation between prevalence and demographic characteristics, smoking and drinking, or type of dyspepsia. Forty subjects with dyspepsia were examined and the specific diagnosis was found in 18 (45%) of them. The subgroup with reflux-like dyspepsia was the largest (60%), although there was considerable overlap between subgroups with reflux-like, ulcer-like and dysmotility-like dyspepsia. Anti-Helicobacter pylori antibodies (IgG) were found in 52% of the subjects, but bacterial infection was not related with dyspepsia.
Up to one-fourth of the general population in the city where the subjects reside may have dyspepsia. This disorder was associated with irritable bowel syndrome in half of the cases, but was not associated with H. pylori infection.
消化不良在社区中的患病率鲜为人知，因为大多数研究使用的样本不具有一般人群的代表性。本研究旨在确定一般人群随机样本中消化不良的患病率及其流行病学和社会人口学特征。
在这项描述性研究中，我们使用在个人访谈期间发放的问卷，对地中海人群中的264名受试者随机样本进行了调查。
消化不良的患病率为24%；我们发现患病率与人口统计学特征、吸烟和饮酒或消化不良类型之间没有关联。对40名消化不良患者进行了检查，其中18名（45%）确诊。反流样消化不良亚组最大（60%），尽管反流样、溃疡样和动力障碍样消化不良亚组之间有相当大的重叠。52%的受试者检测到抗幽门螺杆菌抗体（IgG），但细菌感染与消化不良无关。
受试者居住城市中多达四分之一的一般人群可能患有消化不良。这种疾病在半数病例中与肠易激综合征有关，但与幽门螺杆菌感染无关。
