Hebert A A, Ralston J P
Department of Dermatology, University of Texas at Houston Medical School, USA.
J Clin Psychiatry. 2001;62 Suppl 14:22-6.
Skin eruptions are an important consideration for any clinician who prescribes anticonvulsant medications. The timely recognition and accurate diagnosis of cutaneous reactions can prevent potentially fatal reactions and affect subsequent anticonvulsant treatment options. This review addresses the most common and most serious cutaneous reactions to anticonvulsant medications. The anticonvulsant hypersensitivity syndrome and individual antiepileptic medications that cause severe skin reactions will be reviewed. These reactions include morbilliform and urticarial drug eruptions as well as the erythema multiforme spectrum.
对于任何开具抗惊厥药物的临床医生来说,皮肤疹都是一个重要的考虑因素。及时识别和准确诊断皮肤反应可以预防潜在的致命反应,并影响后续的抗惊厥治疗选择。本综述阐述了对抗惊厥药物最常见和最严重的皮肤反应。将对抗惊厥药物超敏反应综合征以及导致严重皮肤反应的个别抗癫痫药物进行综述。这些反应包括麻疹样和荨麻疹样药疹以及多形红斑谱。