Silva P S, Fonseca M C, Iglesias S B, Carvalho W B, Bussolan R M, Freitas I W
Paediatric Intensive Care Unit, Department of Paediatrics, São Paulo Federal University and Emílio Ribas Infectious Disease Institute, São Paulo, Brazil.
Ann Trop Paediatr. 2001 Jun;21(2):135-40.
Two different illness severity scores, Pediatric Risk of Mortality (PRISM) and the Glasgow Meningococcal Sepsis Prognostic Score (GMSPS), were evaluated and compared in meningococcal disease in two paediatric intensive care units. Forty-nine children with a median age of 36 months who had meningococcal sepsis confirmed by laboratory data were evaluated. Overall mortality was 18%. The median GMSPS was 3 in survivors and 8 in non-survivors. A GMSPS > or = 8 was significantly associated with death (p = 0.0001) with a mortality predictivity and specificity of 70% and 92.5%, respectively. The median PRISM score in survivors was 5.5 and 23 in non-survivors. A PRISM score of > or = 11 was significantly related to death (p < 0.0001). The Kendal correlation co-efficient between GMSPS and PRISM showed tau = 0.6859 (p = 0.0000). It is concluded that GMSPS and PRISM are useful methods for identifying and classifying children into low and high risk categories. GMSPS > or = 8 or a PRISM score > or = 11 are significantly predictive of mortality.
在两个儿科重症监护病房中，对两种不同的疾病严重程度评分系统，即小儿死亡风险（PRISM）评分和格拉斯哥脑膜炎球菌败血症预后评分（GMSPS）进行了评估和比较。对49名年龄中位数为36个月、经实验室数据确诊患有脑膜炎球菌败血症的儿童进行了评估。总体死亡率为18%。存活者的GMSPS中位数为3，非存活者为8。GMSPS≥8与死亡显著相关（p = 0.0001），死亡率预测性和特异性分别为70%和92.5%。存活者的PRISM评分中位数为5.5，非存活者为23。PRISM评分≥11与死亡显著相关（p < 0.0001）。GMSPS与PRISM之间的肯德尔相关系数显示tau = 0.6859（p = 0.0000）。结论是，GMSPS和PRISM是将儿童分为低风险和高风险类别的有用方法。GMSPS≥8或PRISM评分≥11对死亡率有显著预测作用。
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