Ellis R H, Simpson P, Tatham P, Leighton M, Williams J
Anaesthesia. 1975 May;30(3):318-22. doi: 10.1111/j.1365-2044.1975.tb00862.x.
The effects of the intravenous infusion of dantrolene sodium and of equal volumes of normal saline on arterial pressure, central venous pressure, heart rate and cardiac output have been investigated in healthy, anaesthetised dogs. The infusion of dantrolene in the manner and dose found to be effective by other workers in pigs-8 for the treatment of anaesthetic induced malignant hyperpyrexia, produced changes which differ little from those observed after the infusion of a similar quantity of saline. These results are discussed.
在健康的麻醉犬中，研究了静脉输注丹曲林钠和等体积生理盐水对动脉压、中心静脉压、心率和心输出量的影响。按照其他研究人员在猪身上发现的有效方式和剂量8输注丹曲林以治疗麻醉引起的恶性高热，所产生的变化与输注等量生理盐水后观察到的变化几乎没有差异。对这些结果进行了讨论。
