Anderson J G, Clark D R
Am J Vet Res. 1975 Jul;36(7):1037-40.
Adrenalectomized dogs were observed in order to identify the patterns of physiologic changes occurring during development of adrenocortical insufficiency. Daily measurements included plasma concentrations of sodium and potassium, arterial blood pH, packed cell volume, heart rate, and selected components of the electrocardiogram (ECG). The pattern in which these measurements changed indicated that alterations in plasma concentrations of sodium and potassium, T-wave configuration, and QRS interval were more consistent, whereas alterations in P-wave configuration were not evident until approach of terminal stages.
观察肾上腺切除的狗，以确定肾上腺皮质功能不全发展过程中发生的生理变化模式。每日测量包括血浆钠和钾浓度、动脉血pH值、红细胞压积、心率以及心电图（ECG）的选定组成部分。这些测量值变化的模式表明，血浆钠和钾浓度、T波形态以及QRS间期的改变更为一致，而P波形态的改变直到末期才明显。
