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伴有类骨质形成的脊髓弓形虫性蛛网膜炎:一种罕见的弓形虫病表现。

Spinal toxoplasmic arachnoiditis associated with osteoid formation: a rare presentation of toxoplasmosis.

作者信息

Cosan T E, Kabukcuoğlu S, Arslantas A, Atasoy M A, Dogan N, Ozgunes I, Kebabci M, Tel E

机构信息

Department of Neurosurgery, Osmangazi University, Eskisehir, Turkey.

出版信息

Spine (Phila Pa 1976). 2001 Aug 1;26(15):1726-8. doi: 10.1097/00007632-200108010-00019.

Abstract

STUDY DESIGN

An extremely rare presentation of an isolated spinal toxoplasmic arachnoiditis is described.

OBJECTIVE

To draw attention to the fact that spinal arachnoid membranes may be a potential reservoir for Toxoplasma gondii.

SUMMARY OF BACKGROUND DATA

Central nervous system toxoplasmosis is a common manifestation in patients who are immunodeficient. Reports on the spinal toxoplasmosis are rare and focused on spinal cord involvement.

METHODS

An adult patient presented with symptoms of spastic paraparesis that had begun 13 years before admission. Thoracic spinal magnetic resonance imaging showed small lesions in posterior subarachnoid space at Th7-Th8. A Th7-Th8 laminectomy was performed. Intradural-extramedullary lesions were excised.

RESULTS

Clinical, immunologic, and pathologic examinations showed adhesive spinal arachnoiditis associated with osteoid formation caused by past toxoplasmic infection. There was no impairment of the immunologic defense system.

CONCLUSION

Where no causative factor is found in serious spinal adhesive arachnoiditis, the possibility of spinal toxoplasmosis should also be investigated.

摘要

研究设计

描述了一种极为罕见的孤立性脊髓弓形虫性蛛网膜炎表现。

目的

提请注意脊髓蛛网膜可能是弓形虫的潜在储存库这一事实。

背景资料总结

中枢神经系统弓形虫病在免疫缺陷患者中是一种常见表现。关于脊髓弓形虫病的报道罕见,且主要集中在脊髓受累方面。

方法

一名成年患者出现痉挛性截瘫症状,该症状在入院前13年就已开始。胸椎磁共振成像显示胸7 - 胸8水平后蛛网膜下腔有小病变。实施了胸7 - 胸8椎板切除术。切除了硬脊膜外髓外病变。

结果

临床、免疫学和病理学检查显示为既往弓形虫感染所致的伴有类骨质形成的粘连性脊髓蛛网膜炎。免疫防御系统未受损。

结论

在严重的脊髓粘连性蛛网膜炎中若未发现病因,也应调查脊髓弓形虫病的可能性。

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