Liu S, Sato K, Kobayashi T, Yamada T, Kageyama Y, Kihara K
Department of Urology and Reproductive Medicine, Graduate School, Tokyo Medical and Dental University, Bunkyo, Japan.
Auton Neurosci. 2001 Apr 12;88(1-2):45-51. doi: 10.1016/S1566-0702(01)00213-2.
The level of the thoracolumbar sympathetic outflow projecting to the vagina and the laterality of the signals passing through the splanchnic nerves to the vagina have not been well understood. This study was undertaken to explore the sympathetic innervation of the canine vagina by measuring intraluminal pressure of the vagina and contraction of the vaginal wall by electrical stimulation of each of the thoracolumbar splanchnic nerves with or without transection of unilateral hypogastric nerve (HGN). The 2nd-4th lumbar splanchnic nerve (LSN) stimulation elicited elevation of intraluminal pressure of the vagina and contraction of the vaginal wall. In contrast, intermesenteric plexus stimulations caused no response in both the vaginal pressure and the wall itself. On the right side, 12 of 27 LSNs that were stimulated elicited elevation of vaginal pressure and 16 of 32 LSN stimulations caused contraction of the wall, 10 increases in tension and 6 reductions. On the left side, 14 of 26 LSN stimulations elicited elevation of vaginal pressure and 12 of 27 LSN stimulations caused contraction of the wall, 5 increases in tension and 7 reductions. After transection of the right HGN, 6 of 14 right LSN stimulations elicited elevation of vaginal pressure and 10 of 15 right LSN stimulations caused contraction of the wall, 9 increases in tension and 1 reduction. After transection of the left HGN, 13 of 19 left LSN stimulations elicited elevation of vaginal pressure and 10 of 18 left LSN stimulations caused contraction of the wall. 4 increases in tension and 6 reductions. The results indicate that each of the L2-L4 LSNs on either side sends signals to the canine vagina via multiple routes with a crossing site at the level of the caudal mesenteric plexus (CMP).
投射至阴道的胸腰交感神经传出纤维的水平以及通过内脏神经传至阴道的信号的偏向性尚未得到充分了解。本研究旨在通过测量阴道腔内压力以及在切断或未切断单侧腹下神经（HGN）的情况下电刺激每条胸腰内脏神经来探究犬阴道的交感神经支配。刺激第2 - 4腰内脏神经（LSN）可引起阴道腔内压力升高和阴道壁收缩。相比之下，刺激肠系膜间神经丛对阴道压力和阴道壁本身均无反应。右侧，27条受刺激的LSN中有12条引起阴道压力升高，32次LSN刺激中有16次导致阴道壁收缩，10次张力增加，6次张力降低。左侧，26次LSN刺激中有14次引起阴道压力升高，27次LSN刺激中有12次导致阴道壁收缩，5次张力增加，7次张力降低。切断右侧HGN后，14次右侧LSN刺激中有6次引起阴道压力升高，15次右侧LSN刺激中有10次导致阴道壁收缩，9次张力增加，1次张力降低。切断左侧HGN后，19次左侧LSN刺激中有13次引起阴道压力升高，18次左侧LSN刺激中有10次导致阴道壁收缩，4次张力增加，6次张力降低。结果表明，两侧的L2 - L4 LSN均通过多种途径向犬阴道发送信号，交叉部位位于肠系膜尾丛（CMP）水平。
