Tomkiewicz-Pajak L, Olszowska M, Przewłocki T, Sedziwy E, Wilkołek P, Tracz W
Klinika Chorób Serca i Naczyń Instytut Kardiologii Collegium Medicum Uniwersytetu Jagiellońskiego w Krakowie.
Przegl Lek. 2001;58(3):117-9.
The aim of the present study was to examine the effect of exercise test on QT dispersion (dQT) and to compare the result in women with syndrome X with women with coronary artery disease and normal subjects. We examined 53 women in mean age 54.2 +/- 9.2 who were divided into groups: 20 women with one-vessel coronary artery disease (group I), 19 women with syndrome X (group II) and 14 healthy control women (group III). All subjects underwent a modified Bruce protocol exercise test and QT intervals were measured manually at rest and peak exercise. The value of dQT was calculated as a difference between the longest and the shortest measured value in each of the 12 ECG leads. Corrected QT (dQTc) dispersion was measured after the QT interval was corrected with Bazett's formula. There were no significant differences in rest values of dQT between groups but rest dQTc was significantly greater in group I and II then in group III. We observed significant increase in dQT and dQTc on peak exercise in group I and II when compared with group III.
At rest dQTc is significantly greater in women with syndrome X and coronary artery diseases in comparison with control subjects. The exercise caused increase in the value of dQT and dQTc both in women with syndrome X and coronary artery disease. The value of dQT and dQTc makes impossible to differentiate between women with syndrome X and women with coronary artery disease.
本研究的目的是检测运动试验对QT离散度（dQT）的影响，并比较X综合征女性、冠心病女性和正常受试者的结果。我们检查了53名平均年龄为54.2±9.2岁的女性，她们被分为几组：20名单支冠状动脉疾病女性（I组），19名X综合征女性（II组）和14名健康对照女性（III组）。所有受试者均接受改良的布鲁斯方案运动试验，并在静息和运动峰值时手动测量QT间期。dQT值计算为12个心电图导联中每个导联最长和最短测量值之间的差值。在用Bazett公式校正QT间期后测量校正QT（dQTc）离散度。各组间静息dQT值无显著差异，但I组和II组的静息dQTc显著高于III组。与III组相比，我们观察到I组和II组在运动峰值时dQT和dQTc显著增加。
与对照组相比，X综合征和冠心病女性静息时的dQTc显著更高。运动导致X综合征和冠心病女性的dQT和dQTc值增加。dQT和dQTc值无法区分X综合征女性和冠心病女性。
