Tsai W C, Yen J H, Chen C J, Tsai J J, Ou T T, Liu H W
Department of Internal Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
Kaohsiung J Med Sci. 2001 Apr;17(4):212-5.
Familial Mediterranean fever is a rare disease characterized by cyclic attacks of fever, serositis and strong family background. Here we report a 22-year-old man who suffered from recurrent fever accompanied by chest and abdominal pain for more than 10 years. The attack frequency was about once per 2-3 weeks. Although he consulted many clinics and even received appendectomy at the age of 15, no definite diagnosis was given. During the admission, many laboratory examinations failed to show any abnormality except mild leukocytosis and elevated C-reaction protein. Image studies including chest X ray and abdominal CT scan showed negative result but, interestingly, Gallium-67 scan showed a hot spot in right lower chest and right lower abdomen. After prophylaxis with colchicine 1.0 mg per day, he has enjoyed more than 2 years without the above symptoms.
家族性地中海热是一种罕见疾病，其特征为周期性发热、浆膜炎以及明显的家族背景。在此我们报告一名22岁男性，他反复发热并伴有胸腹痛超过10年。发作频率约为每2至3周一次。尽管他曾就诊于多家诊所，甚至在15岁时接受了阑尾切除术，但仍未得到明确诊断。入院期间，许多实验室检查除轻度白细胞增多和C反应蛋白升高外未显示任何异常。包括胸部X线和腹部CT扫描在内的影像学检查结果均为阴性，但有趣的是，镓-67扫描显示右下胸部和右下腹有一个热点。在每天服用1.0毫克秋水仙碱进行预防治疗后，他已两年多未出现上述症状。
