Løvdal T, Berg T
Division of Molecular Cell Biology, Department of Biology, University of Oslo, Oslo, Blindern, 0316, Norway.
Cell Biol Int. 2001;25(8):821-4. doi: 10.1006/cbir.2001.0761.
Expression of Fc(gamma)-receptors (Fc(gamma)Rs) in different liver cells is poorly characterised. In the present study, transcription of Fc(gamma)Rs in different rat liver cells was examined by means of Northern blot analysis and reverse transcriptase-polymerase chain reactions. We found that both Kupffer and liver endothelial cells produce mRNA for Fc(gamma)RIIB2, Fc(gamma)RIII and the gamma-chain, whereas the level of Fc(gamma)RIIB1 mRNA is negligible. In contrast, parenchymal cells produce no Fc(gamma)R mRNA.
不同肝细胞中Fc（γ）受体（Fc（γ）Rs）的表达特征尚不明确。在本研究中，通过Northern印迹分析和逆转录-聚合酶链反应检测了不同大鼠肝细胞中Fc（γ）Rs的转录情况。我们发现，库普弗细胞和肝内皮细胞均产生Fc（γ）RIIB2、Fc（γ）RIII和γ链的mRNA，而Fc（γ）RIIB1 mRNA的水平可忽略不计。相比之下，实质细胞不产生Fc（γ）R mRNA。
