Kaback H R, Sahin-Tóth M, Weinglass A B
Howard Hughes Medical Institute, Department of Physiology, University of California, Los Angeles, California 90095-1662, USA.
Nat Rev Mol Cell Biol. 2001 Aug;2(8):610-20. doi: 10.1038/35085077.
Membrane transport proteins catalyse the movement of molecules into and out of cells and organelles, but their hydrophobic and metastable nature often makes them difficult to study by traditional means. Novel approaches that have been developed and applied to one membrane transport protein, the lactose permease from Escherichia coli, are now being used to study various other membrane proteins.
膜转运蛋白催化分子进出细胞和细胞器，但它们的疏水性和亚稳态性质常常使它们难以用传统方法进行研究。现已开发出并应用于一种膜转运蛋白（来自大肠杆菌的乳糖通透酶）的新方法，正被用于研究各种其他膜蛋白。
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