Aughey E, Scott R, King P C, East B W, Harris I A, Boddy K
Br J Urol. 1975 Apr;47(2):185-91. doi: 10.1111/j.1464-410x.1975.tb03945.x.
The gonadal effects produced by injection of cadmium in the rats are well known. The effects of direct injection into the prostate are less well understood. The present experiments indicated the retention of cadmium by the various lobes of the rat prostate following direct injection of radioactive cadmium into the organ. The cells of the prostate are capable of retaining cadmium in measurable amounts up to at least 6 weeks following the injection. The subcellular fractions were measured with respect to cadmium activity and these are indicated. In addition measurements were made in organs which are known to be affected by cadmium, that is, kidney and the testicle. The affinity of the kidney for cadmium is confirmed. The areas of the prostate gland with a high zinc content appear to retain less cadmium than areas of the gland which are known to have a low zinc content. This suggests a possible zinc protective mechanism.
注射镉对大鼠性腺产生的影响是众所周知的。而直接注射到前列腺中的影响则了解较少。目前的实验表明，将放射性镉直接注射到大鼠前列腺器官后，镉在前列腺各叶中的留存情况。注射后，前列腺细胞能够留存可测量量的镉，至少持续6周。对亚细胞部分的镉活性进行了测量，并给出了测量结果。此外，还对已知受镉影响的器官，即肾脏和睾丸进行了测量。证实了肾脏对镉的亲和力。锌含量高的前列腺区域似乎比已知锌含量低的区域留存的镉更少。这表明可能存在锌保护机制。
