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病例报告。血液系统恶性肿瘤治疗后侵袭性曲霉病采用脂质体两性霉素B进行二级预防。

Case reports. Secondary prophylaxis with liposomal amphotericin B after invasive aspergillosis following treatment for haematological malignancy.

作者信息

Mele L, Pagano L, Equitani F, Leone G

出版信息

Mycoses. 2001;44(5):201-3. doi: 10.1046/j.1439-0507.2001.00644.x.

DOI:10.1046/j.1439-0507.2001.00644.x
PMID:11486459
Abstract

We report our recent experience with two cases of invasive pulmonary aspergillosis in patients who were both undergoing chemotherapy, one for acute myeloid leukaemia and the other for primary amyloidosis. Both patients had bad prognostic factors and were in very poor clinical condition, but both recovered from infection after a prolonged therapy with liposomal amphotericin B (AmBisome) without signs of toxicity.

摘要

我们报告了最近两例侵袭性肺曲霉病患者的治疗经验,这两名患者均在接受化疗,一名患有急性髓细胞白血病,另一名患有原发性淀粉样变性。两名患者均具有不良预后因素,临床状况极差,但在接受脂质体两性霉素B(安必素)长期治疗后均从感染中康复,且无毒性迹象。

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Invasive coinfection with Aspergillus and Mucor in a patient with acute myeloid leukemia.急性髓系白血病患者侵袭性曲霉和毛霉合并感染。
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Weekly liposomal amphotericin B as secondary prophylaxis for invasive fungal infections in patients with hematological malignancies.
每周脂质体两性霉素 B 作为血液恶性肿瘤患者侵袭性真菌感染的二级预防。
Med Mycol. 2012 Jul;50(5):543-8. doi: 10.3109/13693786.2011.631152. Epub 2011 Nov 22.