儿童白血病中 b 型流感嗜血杆菌血清学：一项病例对照研究。
Haemophilus influenzae type b serology in childhood leukaemia: a case-control study.
作者信息
Groves F D, Sinha D, Kayhty H, Goedert J J, Levine P H
机构信息
Department of Biometry and Epidemiology, Medical University of South Carolina, Charleston, South Carolina, USA.
出版信息
Br J Cancer. 2001 Aug 3;85(3):337-40. doi: 10.1054/bjoc.2001.1903.
Antibody to Haemophilus influenzae type b (Hib) polysaccharide (PRP) was measured in 42 children with acute lymphoblastic leukaemia (ALL) and 42 non-leukaemic hospital controls. Modelling anti-PRP concentrations as a function of age revealed that the slopes of the trend lines differed significantly between cases and controls (P = 0.05); anti-PRP concentrations were lower among younger cases, and higher among older cases, than among controls of the same ages.
在42名急性淋巴细胞白血病（ALL）患儿和42名非白血病住院对照儿童中检测了抗b型流感嗜血杆菌（Hib）多糖（PRP）抗体。将抗PRP浓度作为年龄的函数进行建模，结果显示病例组和对照组的趋势线斜率存在显著差异（P = 0.05）；与相同年龄的对照组相比，年龄较小的病例组抗PRP浓度较低，年龄较大的病例组抗PRP浓度较高。
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