隐匿性甲状腺滤泡癌酷似三叉神经鞘瘤的孤立性转移——病例报告

Solitary metastasis from occult follicular carcinoma of the thyroid mimicking trigeminal neurinoma--case report.

作者信息

Kachhara R, Nair S, Radhakrishnan V V, Pandey M, Ahmed M I, Kumar A, Bhattacharya R N

机构信息

Department of Neurosurgery, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, India.

出版信息

Neurol Med Chir (Tokyo). 2001 Jul;41(7):360-3. doi: 10.2176/nmc.41.360.

DOI:10.2176/nmc.41.360

PMID:11488002

Abstract

A 50-year-old woman presented with an extremely uncommon case of solitary metastasis from follicular carcinoma of the thyroid, which presented clinically as trigeminal neurinoma. Neuroimaging detected a tumor in the right petrous apex, which was removed surgically. Histological examination showed metastatic follicular carcinoma of the thyroid. However, no primary tumor was detected by various investigations. The tumor recurred twice, and was treated surgically both times. The patient finally agreed to adjuvant therapy for the suspected primary. Radiotherapy was performed followed by complete thyroidectomy. Examination of the gross specimen found the tumor nodule. Clinically significant metastasis can arise from histologically benign and silent follicular thyroid neoplasms.

摘要

一名50岁女性出现了极为罕见的甲状腺滤泡癌孤立性转移病例，临床上表现为三叉神经鞘瘤。神经影像学检查发现右侧岩尖有一个肿瘤，遂进行了手术切除。组织学检查显示为甲状腺转移性滤泡癌。然而，通过各种检查均未发现原发肿瘤。肿瘤复发了两次，均进行了手术治疗。患者最终同意对疑似原发灶进行辅助治疗。先进行了放射治疗，随后进行了全甲状腺切除术。对大体标本的检查发现了肿瘤结节。具有临床意义的转移可能源于组织学上良性且无症状的甲状腺滤泡性肿瘤。