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通过放置自膨式支架治疗左半结肠肿瘤性梗阻。

Treatment of left colon neoplasic obstruction by placement of self-expandable stents.

作者信息

Montes López C, Romeo Martínez J M, Tejero Cebrián E, Rábago Torres L, Marinelli Ibarreta A, Vázquez Echarri J, Fernández Lobato R, Castro J L, Martínez Veiga J L

机构信息

Digestive and General Surgery Service, Hospital Severo Ochoa, Leganés, Madrid, Spain.

出版信息

Rev Esp Enferm Dig. 2001 Apr;93(4):226-37.

Abstract

INTRODUCTION AND OBJECTIVE

Neoplasic stenoses of the left colon are most frequently caused by primary colon carcinoma, infiltration from an external tumour and great adenomatous polyps. These patients often develop obstruction as their first symptom, leading to emergency surgical procedures in adverse circumstances and without an appropriate intestinal preparation that might prevent primary anastomosis. Therapeutic options for this event, such as Hartmann's resection, subtotal colectomy or anterograde colon lavage are not always possible. In these patients a colostomy is performed that requires future reoperation for reconstruction of the intestinal transit. Transtumoral self-expandable stenting followed by elective surgery might be the best option in these cases, as well as an alternative to surgery in non-operable patients.

PATIENTS AND METHODS

Twenty four patients treated with this procedure in the past four years were divided in two groups. In group 1 (14 patients), the stent was placed as a permanent and palliative measure for the management of the disease. In group 2 (10 patients), the stent was placed temporarily for the management of the intestinal obstruction and latter the patients underwent elective surgery with fully preoperative and extension study and an appropriate preparation of the colon in order to allow reliable primary anastomosis.

RESULTS

There were no hospital mortality nor stent migrations. There was only one complication (perforation caused by the stent) that required emergency surgery, but with any further complications. Failure to place the stent occurred in one patient.

CONCLUSIONS

Self-expandable stents relieve neoplasic colon obstructions and allow to complete the study protocol, followed by elective surgery associated to less morbi-mortality. In patients with advanced or irresectable cancer, they provide a palliative and safe alternative to surgery, with satisfactory results.

摘要

引言与目的

左半结肠癌性狭窄最常见的病因是原发性结肠癌、外部肿瘤浸润以及巨大腺瘤性息肉。这些患者常以肠梗阻为首发症状,导致在不利情况下进行急诊手术,且缺乏可能预防一期吻合的适当肠道准备。针对这种情况的治疗选择,如哈特曼切除术、结肠次全切除术或顺行结肠灌洗并不总是可行的。在这些患者中会进行结肠造口术,这需要日后再次手术以重建肠道通路。肿瘤内自膨式支架置入后择期手术可能是这些病例的最佳选择,也是无法手术患者手术的替代方案。

患者与方法

过去四年中接受该手术治疗的24例患者分为两组。第1组(14例患者),将支架作为疾病管理的永久性姑息措施置入。第2组(10例患者),支架临时置入以处理肠梗阻,随后患者接受择期手术,进行全面的术前及扩展检查,并对结肠进行适当准备,以实现可靠的一期吻合。

结果

无医院死亡病例,也无支架移位情况。仅发生1例并发症(支架导致的穿孔),需急诊手术,但未出现进一步并发症。1例患者支架置入失败。

结论

自膨式支架可缓解结肠癌性梗阻,使研究方案得以完成,随后进行择期手术,且手术相关的病残率和死亡率较低。对于晚期或无法切除的癌症患者,它们为手术提供了一种姑息性且安全的替代方案,效果令人满意。

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