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恶性大肠梗阻患者近端结肠支架置入术:技术与结果

Stenting of the proximal colon in patients with malignant large bowel obstruction: techniques and outcomes.

作者信息

Repici Alessandro, Adler Douglas G, Gibbs Christopher M, Malesci Alberto, Preatoni Paoletta, Baron Todd H

机构信息

Instituto Clinico Humanitas, Milan, Italy.

出版信息

Gastrointest Endosc. 2007 Nov;66(5):940-4. doi: 10.1016/j.gie.2007.04.032.

Abstract

BACKGROUND

Self-expandable metal stents are used throughout the GI tract to relieve malignant obstructions.

OBJECTIVE

Our purpose was to determine the outcome after colonic stent placement into the proximal colon.

DESIGN

Medical records of patients from 3 institutions who underwent attempts at placement of self-expandable metal stents for malignant obstructions of the proximal colon were retrospectively reviewed. Extracted data included patient characteristics, obstruction location, and goal of procedure (palliation vs bridge to surgery).

SETTING

Academic medial centers.

PATIENTS

Those with right-sided malignant colonic obstruction.

INTERVENTIONS

Placement of colonic stent.

MAIN OUTCOME MEASUREMENTS

Initial technical success, relief of obstruction, and early and long-term complications.

RESULTS

Twenty-one patients (15 men, 6 women; mean age 67 years) were included. Tumor type was colonic adenocarcinoma in 19 patients. Obstruction was complete in 8 patients and subtotal in 13 patients. Stenting was attempted as a bridge to surgery in 8 patients and as palliation in 13 patients. Initial technical success was achieved in 20 of 21 patients (95%). Complete relief of obstruction was achieved in 17 of 20 patients who had technical success (85%), unachieved in 2 patients (No. 14 and 17), and unknown in 1 patient (No. 6). There were no procedure-related complications (bleeding, perforation, etc). The only long-term complication was stent reocclusion from tumor ingrowth.

LIMITATIONS

Retrospective, single-arm analysis.

CONCLUSIONS

Self-expandable metal stents appear to be safe and effective in the treatment of malignant obstruction of the proximal colon. Technical and clinical success rates are comparable to those seen with distal colonic stenting.

摘要

背景

自膨式金属支架用于全胃肠道以缓解恶性梗阻。

目的

我们的目的是确定将结肠支架置入近端结肠后的结果。

设计

对来自3家机构的患者的医疗记录进行回顾性分析,这些患者因近端结肠恶性梗阻而尝试置入自膨式金属支架。提取的数据包括患者特征、梗阻部位以及手术目的(姑息治疗与手术过渡)。

地点

学术医学中心。

患者

右侧结肠恶性梗阻患者。

干预措施

放置结肠支架。

主要观察指标

初始技术成功率、梗阻缓解情况以及早期和长期并发症。

结果

纳入21例患者(15例男性,6例女性;平均年龄67岁)。19例患者的肿瘤类型为结肠腺癌。8例患者为完全性梗阻,13例患者为不全性梗阻。8例患者尝试将支架置入作为手术过渡,13例患者作为姑息治疗。21例患者中有20例(95%)获得初始技术成功。20例技术成功的患者中有17例(85%)实现了梗阻完全缓解,2例患者(第14例和第17例)未实现,1例患者(第6例)情况未知。无手术相关并发症(出血、穿孔等)。唯一的长期并发症是肿瘤长入导致支架再闭塞。

局限性

回顾性单臂分析。

结论

自膨式金属支架在治疗近端结肠恶性梗阻方面似乎安全有效。技术成功率和临床成功率与远端结肠支架置入相当。

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