Spreer J, Quiske A, Altenmüller D M, Arnold S, Schulze-Bonhage A, Steinhoff B J, Schumacher M
Sections of Neuroradiology and Presurgical Epilepsy Diagnosis, University Hospital Freiburg, Freiburg, Germany.
Epilepsia. 2001 Jul;42(7):957-9. doi: 10.1046/j.1528-1157.2001.042007957.x.
We sought to illustrate the value of functional magnetic resonance imaging (fMRI) in the presurgical assessment of hemispheric dominance for language by means of an illustrative case report.
fMRI with two language paradigms was performed in a right-handed patient without familial sinistrality suffering from a left frontal focal epilepsy.
Both fMRI paradigms revealed unequivocally lateralized right hemispheric activation. Atypical language representation was confirmed by Wada test. The further presurgical workup could be restricted to subdural strip recordings instead of the initially intended grid implantation. After resective surgery, no language deficits were apparent.
Hemispheric dominance for language should be assessed by fMRI in all patients before surgery in areas potentially relevant for language in either cerebral hemisphere. fMRI may influence the further diagnostic workup and should be performed before other invasive diagnostic procedures.
我们试图通过一个病例报告来说明功能磁共振成像（fMRI）在术前评估半球语言优势方面的价值。
对一名无家族左利手的右利手患者进行了两种语言范式的fMRI检查，该患者患有左侧额叶局灶性癫痫。
两种fMRI范式均明确显示右侧半球激活。Wada试验证实了非典型语言表征。进一步的术前检查可限于硬膜下条状记录，而不是最初计划的网格植入。切除术后，未出现明显的语言缺陷。
对于所有患者，在手术前应对大脑半球中任何可能与语言相关的区域进行fMRI语言优势半球评估。fMRI可能会影响进一步的诊断检查，应在其他侵入性诊断程序之前进行。
