Suri P K, Johnston D W
Can J Surg. 1975 Jul;18(4):361-3.
The incidence of postoperative wound infection was studied in relation to 146 surgical wounds in patients who received cephaloridine as prophylactic antibacterial therapy, and in relation to 120 wounds in another group of patients who did not receive cephaloridine. In the first group, 5 of 146 (3.4%) of wounds became infected; in the second, 25 of 120 (20.8%) of wounds became infected. The difference between the two groups is significant. Use of cephaloridine in this series of patients therefore decreased the incidence of postoperative wound infection.
研究了接受头孢菌素作为预防性抗菌治疗患者的146处手术伤口的术后伤口感染发生率，并与另一组未接受头孢菌素治疗患者的120处伤口进行对比。在第一组中，146处伤口中有5处（3.4%）感染；在第二组中，120处伤口中有25处（20.8%）感染。两组之间的差异具有统计学意义。因此，在这组患者中使用头孢菌素降低了术后伤口感染的发生率。
