使用放射性核素食管排空试验评估贲门失弛缓症的气囊扩张效果。
Using radionuclide esophageal emptying test to evaluate pneumatic dilatation effects for achalasia.
作者信息
Shen Y Y, Shiau Y C, Sun S S, Kao C H
机构信息
Department of Nuclear Medicine, Shin Kong Wu Ho-Su Memorial Hospital, Taipei.
出版信息
Hepatogastroenterology. 2001 Jul-Aug;48(40):1061-3.
BACKGROUND/AIMS: Radionuclide esophageal emptying test using a solid meal is a simple, noninvasive, and physiologic test of esophageal function.
METHODOLOGY
In this study, we evaluated esophageal emptying using an isotope-labeled solid meal (an egg salad sandwich labeled with 99mTc-MAA) in the assessment of pneumatic dilatation treatment in achalasia. Twenty achalasic patients (12 males, 8 females, age: 51.4 +/- 13.0 years) underwent esophageal emptying measurement before and after pneumatic dilatation. After treatment, the dysphagic symptoms of all patients improved.
RESULTS
In comparison with the pretreatment test, the posttreatment retention fraction at 1, 5, 10, and 15 min were significantly lower (P < 0.001).
CONCLUSIONS
The results suggest that radionuclide esophageal emptying test using a solid meal remains a useful objective study of esophageal function and may have an important future role in the follow-up evaluation of treatment for achalasia.
背景/目的：使用固体食物的放射性核素食管排空试验是一种简单、无创且生理性的食管功能检查。
方法
在本研究中，我们使用同位素标记的固体食物（用99mTc-MAA标记的鸡蛋沙拉三明治）评估食管排空，以用于贲门失弛缓症的气囊扩张治疗评估。20例贲门失弛缓症患者（12例男性，8例女性，年龄：51.4±13.0岁）在气囊扩张前后进行了食管排空测量。治疗后，所有患者的吞咽困难症状均有改善。
结果
与治疗前试验相比，治疗后1、5、10和15分钟时的潴留分数显著降低（P<0.001）。
结论
结果表明，使用固体食物的放射性核素食管排空试验仍是一项有用的食管功能客观研究，可能在贲门失弛缓症治疗的随访评估中发挥重要的未来作用。
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