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改良Sugiura手术在静脉曲张出血管理中的当前适应证

Current indication of a modified Sugiura procedure in the management of variceal bleeding.

作者信息

Selzner M, Tuttle-Newhall J E, Dahm F, Suhocki P, Clavien P A

机构信息

Department of Visceral Surgery and Transplantation, Universitätsspital, Zürich, Switzerland.

出版信息

J Am Coll Surg. 2001 Aug;193(2):166-73. doi: 10.1016/s1072-7515(01)00937-1.

Abstract

BACKGROUND

The role of gastroesophageal devascularization (Sugiura-rype procedures) for the treatment of variceal bleeding remains controversial. Although Japanese series reported favorable longterm results, the technique has nor been widely accepted in the Western Hemisphere because of a high postoperative morbidity and mortality. The reasons for the different outcomes are unclear. In a multidisciplinary team approach we developed a therapeutic algorithm for patients with recurrent variceal bleeding.

STUDY DESIGN

The Sugiura procedure was offered only to patients with well-preserved liver function (Child A or Child B cirrhosis without chronic ascites) who were not candidates for distal splenorenal shunt, transhepatic porto-systemic shunt, or liver transplantation.

RESULTS

Fifteen patients with recurrent variceal bleeding underwent a modified Sugiura procedure between September 1994 and September 1997. All but one patient (operative mortality 7%) are alive after a median followup of 4 years. Recurrent variceal bleeding developed in one patient; esophageal strictures, which were successfully treated by endoscopic dilatation, developed in three patients; and one patient experienced mild encephalopathy. Major complications were noted only in patients with impaired liver function (Child B cirrhosis) or when the modified Sugiura was performed in an emergency setting. The presence of cirrhosis or the cause of portal hypertension had no significant impact on the complication rate.

CONCLUSIONS

This series was performed during the last decade when all modern therapeutic options for variceal bleeding were available. Our results indicate that the modified Sugiura procedure is an effective rescue therapy in patients who are not candidates for selective shunts, transhepatic porto-systemic shunt, or transplantation. Emergency settings and decreased liver function are associated with an increased morbidity.

摘要

背景

胃食管去血管化术(杉浦式手术)在治疗静脉曲张出血中的作用仍存在争议。尽管日本的系列报道显示长期效果良好,但由于术后发病率和死亡率较高,该技术在西半球尚未被广泛接受。不同结果的原因尚不清楚。我们采用多学科团队方法,为复发性静脉曲张出血患者制定了一种治疗算法。

研究设计

仅向肝功能良好(Child A级或无慢性腹水的Child B级肝硬化)且不适合行远端脾肾分流术、经肝门静脉系统分流术或肝移植的患者提供杉浦手术。

结果

1994年9月至1997年9月期间,15例复发性静脉曲张出血患者接受了改良杉浦手术。除1例患者(手术死亡率7%)外,所有患者在中位随访4年后均存活。1例患者出现复发性静脉曲张出血;3例患者出现食管狭窄,经内镜扩张成功治疗;1例患者出现轻度脑病。主要并发症仅见于肝功能受损(Child B级肝硬化)的患者或在紧急情况下进行改良杉浦手术的患者。肝硬化的存在或门静脉高压的病因对并发症发生率无显著影响。

结论

本系列研究是在过去十年中进行的,当时所有现代静脉曲张出血治疗选择均已可用。我们的结果表明,改良杉浦手术对于不适合选择性分流术、经肝门静脉系统分流术或移植的患者是一种有效的挽救治疗方法。紧急情况和肝功能下降与发病率增加相关。

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